Calcium channel blockers (versus unexposed)

Atresia or stenosis of other parts of small intestine

id	Study   Auto Fisher a - Calcium blockers, 2018Sorensen - Calcium blockers, 2001	Lib. in paper	Exposition period  Auto during pregnancy (anytime or not specified)1st trimester2nd trimester3rd trimester2nd and/or 3rd trimesterthroughout pregnancyearly pregnancydays before deliverylate pregnancypreconception-onlypericonceptionalpreconceptional for kinetic reasonat least 1st trimester3 months (or more) before pregnancy or during pregnancy1st and 2nd trimester3 months or more before pregnancy or1st trimester	Study type  All studies Case control excluded Only case control	Control type    Auto unexposed (general population or NOS)unexposed, sickunexposed, disease freeexposed to other treatment, sicknot specifiedsiblingwhatever (meta-analysis)	Tags	OR 95%CI	x1/n1 x0/n0	no cases	no exposed	ROB	Ref.
S13787 R54031	Fisher a - Calcium blockers, 2018	Small intestinal atresia/stenosis	1st trimester	case control	unexposed, disease free	Adjustment: Yes Indications Antihypertensive: All hypertensions, any indications or not specified	11.20 [3.70;34.20]	7/21   420/10,977	427	21		ref
S13996 R54985	Sorensen - Calcium blockers, 2001	Intestinal atresia/stenosis	1st trimester	case control	unexposed (general population or NOS)	Adjustment: No Indications Antihypertensive: All hypertensions, any indications or not specified	2.56 [0.16;41.65] C	0/49   151/38,253	151	49		ref
					Total	2 studies	9.15 [3.26;25.70]		578	70
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

Sensitivity analysis

Publication bias and p-hacking diagnosis

Sub-groups analysis using all included studies

excluded