Antimycotic Azoles (all routes except local only) updated on 01-29-2025

Pulmonary artery stenosis

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S17735
R74928		 Molgaard-Nielsen - Fluconazole, 2013 Pulmonary-artery hypoplasia 1st trimester population based cohort retrospective unexposed (general population or NOS) Adjustment: No Fluconazole not specified or mixed dose 26.34 [1.26;548.75] C 0/7,352   2/968,236 2 7,352
ref
Total 1 studies 26.34 [1.26;548.75] 2 7,352
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Molgaard-Nielsen - Fluconazole, 2013Molgaard-Nielsen - Fluconazole, 2013 26.34[1.26; 548.75]27,3520%ROB confusion: criticalROB selection: lowROB classification: moderateROB missing: lowROB mesure: moderateROB reporting: moderate0.9100.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 26.34[1.26; 548.75]27,352 -NAMolgaard-Nielsen - Fluconazole, 2013 1 case control studiescase control studies 0 Type of controls unexposed (disease free or unspecified)unexposed (disease free or unspecified) 26.34[1.26; 548.75]27,352 -NAMolgaard-Nielsen - Fluconazole, 2013 1 Tags Adjustment   - No  - No 26.34[1.26; 548.75]27,352 -NAMolgaard-Nielsen - Fluconazole, 2013 1 Fluconazole not specified or mixed doseFluconazole not specified or mixed dose 26.34[1.26; 548.75]27,352 -NAMolgaard-Nielsen - Fluconazole, 2013 1 All studiesAll studies 26.34[1.26; 548.75]27,352 -NAMolgaard-Nielsen - Fluconazole, 2013 10.5100.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) Out of scale26.34[1.26; 548.75]27,352 -NAMolgaard-Nielsen - Fluconazole, 2013 10.510.01.0