Omeprazole updated on 08-09-2023

Perinatal death

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S4548
R10998		 Källén, 2001 Perinatally dead at least 1st trimester population based cohort retrospective unexposed (general population or NOS) Adjustment: No 1.66 [0.70;3.98] 5/863   -/- - 863
ref
Total 1 studies 1.66 [0.70;3.96] 0 863
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Källén, 2001Källén, 2001 1.66[0.70; 3.98]-8630%ROB confusion: NAROB selection: NAROB classification: NAROB missing: NAROB mesure: NAROB reporting: NA0.55.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 1.66[0.70; 3.96]-863 -NAKällén, 2001 1 case control studiescase control studies 0 Type of controls unexposed (disease free or unspecified)unexposed (disease free or unspecified) 1.66[0.70; 3.96]-863 -NAKällén, 2001 1 Tags Adjustment   - No  - No 1.66[0.70; 3.96]-863 -NAKällén, 2001 1 All studiesAll studies 1.66[0.70; 3.96]-863 -NAKällén, 2001 10.55.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 1.66[0.70; 3.96]-863 -NAKällén, 2001 10.510.01.0