Escitalopram updated on 07-01-2025

Therapeutic terminations of pregnancy

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S6190
R16312		 Klieger-Grossmann, 2012 Therapeutic abortion during pregnancy (anytime or not specified) prospective cohort unexposed (general population or NOS) Adjustment: No Matched Monotherapy: substance alone among all Antidep (SSRI, SNRI, ...) 6.12 [0.73;51.24] C 6/213   1/212 7 213
ref
Total 1 studies 6.12 [0.73;51.24] 7 213
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Klieger-Grossmann, 2012Klieger-Grossmann, 2012 6.12[0.73; 51.24]72130%ROB confusion: criticalROB selection: moderateROB classification: moderateROB missing: unclearROB mesure: moderateROB reporting: moderate0.920.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 6.12[0.73; 51.24]7213 -NAKlieger-Grossmann, 2012 1 case control studiescase control studies 0 Type of controls unexposed (disease free or unspecified)unexposed (disease free or unspecified) 6.12[0.73; 51.24]7213 -NAKlieger-Grossmann, 2012 1 Tags Adjustment   - No  - No 6.12[0.73; 51.24]7213 -NAKlieger-Grossmann, 2012 1 MatchedMatched 6.12[0.73; 51.24]7213 -NAKlieger-Grossmann, 2012 1 Monotherapy   - substance alone among all Antidep ( ...  - substance alone among all Antidep (SSRI, SNRI, ...) 6.12[0.73; 51.24]7213 -NAKlieger-Grossmann, 2012 1 All studiesAll studies 6.12[0.73; 51.24]7213 -NAKlieger-Grossmann, 2012 10.520.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 6.12[0.73; 51.24]7213 -NAKlieger-Grossmann, 2012 10.510.01.0