Clonazepam (Epilepsy) updated on 02-10-2025

Assisted deliveries (forceps, vacuum, ...)

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S8222
R25752		 Endo (Epilepsy) (Controls unexposed, disease free), 2004 Forceps deliveries throughout pregnancy retrospective cohort unexposed, disease free excluded Adjustment: No 11.26 [0.22;573.27] C
excluded (control group) 		0/1   53/656 53 1
ref
S8224
R25782		 Endo (Epilepsy) (Controls unexposed, sick), 2004 Forceps deliveries throughout pregnancy retrospective cohort unexposed, sick Adjustment: No 1.00 [0.00;255.63] C 0/1   0/1 0 1
ref
Total 1 studies 1.00 [0.00;255.63] 0 1
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Endo (Epilepsy) (Controls unexposed, sick), 2004Endo, 2004 1 1.00[0.00; 255.63]010%ROB confusion: criticalROB selection: unclearROB classification: criticalROB missing: lowROB mesure: moderateROB reporting: moderate0.52.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

1: Epilepsy) (Controls unexposed, sick;

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 1.00[0.00; 255.63]-1 -NAEndo (Epilepsy) (Controls unexposed, sick), 2004 1 case control studiescase control studies 0 Type of controls unexposed, sickunexposed, sick 1.00[0.00; 255.63]-1 -NAEndo (Epilepsy) (Controls unexposed, sick), 2004 1 Tags Adjustment   - No  - No 1.00[0.00; 255.63]-1 -NAEndo (Epilepsy) (Controls unexposed, sick), 2004 1 All studiesAll studies 1.00[0.00; 255.63]-1 -NAEndo (Epilepsy) (Controls unexposed, sick), 2004 10.510.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded 8222

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) Out of scale11.26[0.22; 573.27]531 -NAEndo (Epilepsy) (Controls unexposed, disease free), 2004 1 unexposed, sick controlsunexposed, sick controls 1.00[0.00; 255.63]-1 -NAEndo (Epilepsy) (Controls unexposed, sick), 2004 10.510.01.0