Oxcarbazepine (Epilepsy) updated on 04-22-2025

Elective/induced termination of pregnancy

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S12888
R48702		 Hosny (Oxcarbazepine) (Controls exposed to Lamotrigine, sick), 2021 Induced abortion 1st trimester prospective cohort exposed to other treatment, sick excluded Adjustment: No 0.20 [0.00;28.47] C
excluded (control group) 		0/3   0/1 0 3
ref
S12889
R48705		 Hosny (Oxcarbazepine) (Controls unexposed, sick), 2021 Induced abortion 1st trimester prospective cohort unexposed, sick Adjustment: No 8.20 [0.13;511.93] C 0/3   0/21 0 3
ref
Total 1 studies 8.20 [0.13;511.93] 0 3
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Hosny (Oxcarbazepine) (Controls unexposed, sick), 2021Hosny, 2021 1 8.20[0.13; 511.93]030%ROB confusion: criticalROB selection: moderateROB classification: unclearROB missing: lowROB mesure: unclearROB reporting: moderate0.920.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

1: Oxcarbazepine) (Controls unexposed, sick;

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 8.20[0.13; 511.93]-3 -NAHosny (Oxcarbazepine) (Controls unexposed, sick), 2021 1 case control studiescase control studies 0 Type of controls unexposed, sickunexposed, sick 8.20[0.13; 511.93]-3 -NAHosny (Oxcarbazepine) (Controls unexposed, sick), 2021 1 Tags Adjustment   - No  - No 8.20[0.13; 511.93]-3 -NAHosny (Oxcarbazepine) (Controls unexposed, sick), 2021 1 All studiesAll studies 8.20[0.13; 511.93]-3 -NAHosny (Oxcarbazepine) (Controls unexposed, sick), 2021 10.520.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded 12888

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed, sick controlsunexposed, sick controls 8.20[0.13; 511.93]-3 -NAHosny (Oxcarbazepine) (Controls unexposed, sick), 2021 1 exposed to other treatment, sick controlsexposed to other treatment, sick controls Out of scale0.20[0.00; 28.47]-3 -NAHosny (Oxcarbazepine) (Controls exposed to Lamotrigine, sick), 2021 10.510.01.0