Phenobarbital (Epilepsy)

Neonatal medical care

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S6686
R18633		 D'Souza (Phenobarbital) (Controls unexposed, disease free), 1991 Idiopathic respiratory distress throughout pregnancy prospective cohort unexposed, disease free excluded Adjustment: No Matched 17.57 [0.30;1024.08] C
excluded (control group) 		0/4   0/62 0 4
ref
S6694
R18794		 D'Souza (Phenobarbital) (Controls unexposed, sick), 1991 Idiopathic respiratory distress throughout pregnancy prospective cohort unexposed, sick Adjustment: No 2.14 [0.03;131.94] C 0/4   0/8 0 4
ref
Total 1 studies 2.14 [0.03;131.94] 0 4
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF D'Souza (Phenobarbital) (Controls unexposed, sick), 1991D'Souza, 1991 1 2.14[0.03; 131.94]040%ROB confusion: NAROB selection: NAROB classification: NAROB missing: NAROB mesure: NAROB reporting: NA0.95.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

1: Phenobarbital) (Controls unexposed, sick;

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 2.14[0.03; 131.94]-4 -NAD'Souza (Phenobarbital) (Controls unexposed, sick), 1991 1 case control studiescase control studies 0 Type of controls unexposed, sickunexposed, sick 2.14[0.03; 131.94]-4 -NAD'Souza (Phenobarbital) (Controls unexposed, sick), 1991 1 Tags Adjustment   - No  - No 2.14[0.03; 131.94]-4 -NAD'Souza (Phenobarbital) (Controls unexposed, sick), 1991 1 All studiesAll studies 2.14[0.03; 131.94]-4 -NAD'Souza (Phenobarbital) (Controls unexposed, sick), 1991 10.55.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded 6686

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) Out of scale17.57[0.30; 1024.08]-4 -NAD'Souza (Phenobarbital) (Controls unexposed, disease free), 1991 1 unexposed, sick controlsunexposed, sick controls 2.14[0.03; 131.94]-4 -NAD'Souza (Phenobarbital) (Controls unexposed, sick), 1991 10.510.01.0