Trimethadione (Epilepsy = All indications) updated on 04-22-2025

Polydactyly

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S6504
R17903		 Bànhidy (Trimethadione), 2011 Poly/syndactyly throughout pregnancy case control unexposed, sick Adjustment: No Matched 5.00 [0.21;117.90] C 1/2   2/12 3 2
ref
Total 1 studies 5.00 [0.21;117.90] 3 2
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Bànhidy (Trimethadione), 2011Bànhidy, 2011 1 5.00[0.21; 117.90]320%ROB confusion: criticalROB selection: criticalROB classification: lowROB missing: lowROB mesure: moderateROB reporting: moderate0.910.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

1: Trimethadione;

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 0 case control studiescase control studies 5.00[0.21; 117.90]32 -NABànhidy (Trimethadione), 2011 1 Type of controls unexposed, sickunexposed, sick 5.00[0.21; 117.90]32 -NABànhidy (Trimethadione), 2011 1 Tags Adjustment   - No  - No 5.00[0.21; 117.90]32 -NABànhidy (Trimethadione), 2011 1 MatchedMatched 5.00[0.21; 117.90]32 -NABànhidy (Trimethadione), 2011 1 All studiesAll studies 5.00[0.21; 117.90]32 -NABànhidy (Trimethadione), 2011 10.510.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed, sick controlsunexposed, sick controls 5.00[0.21; 117.90]32 -NABànhidy (Trimethadione), 2011 10.510.01.0