Norsuximidium (Epilepsy = ALL)

Major congenital malformations

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S6478
R17755		 Czeizel (Norsuximidium), 1992 Congenital abnormalities throughout pregnancy case control unexposed, sick Adjustment: No 1.15 [0.03;38.88] C 1/1   7/10 8 1
ref
Total 1 studies 1.15 [0.03;38.88] 8 1
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Czeizel (Norsuximidium), 1992Czeizel, 1992 1 1.15[0.03; 38.88]810%ROB confusion: NAROB selection: NAROB classification: NAROB missing: NAROB mesure: NAROB reporting: NA0.55.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

1: Norsuximidium;

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 0 case control studiescase control studies 1.15[0.03; 38.88]81 -NACzeizel (Norsuximidium), 1992 1 Type of controls unexposed, sickunexposed, sick 1.15[0.03; 38.88]81 -NACzeizel (Norsuximidium), 1992 1 Tags Adjustment   - No  - No 1.15[0.03; 38.88]81 -NACzeizel (Norsuximidium), 1992 1 All studiesAll studies 1.15[0.03; 38.88]81 -NACzeizel (Norsuximidium), 1992 10.55.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed, sick controlsunexposed, sick controls 1.15[0.03; 38.88]81 -NACzeizel (Norsuximidium), 1992 10.510.01.0