Lacosamide (All indications) - Medication and Pregnancy KB

Lacosamide (All indications) updated on 04-22-2025

Small for gestational age (weight)

R analysis

id	Study	Lib. in paper	Exposition period	Study type All studies Case control excluded Only case control	Control type	Tags	OR 95%CI	x1/n1 x0/n0	no cases	no exposed	ROB	Ref.
S16193 R79510	The NAAED (Controls exposed to LTG) (Indications NOS), 2025	Small for gestational age	at least 1st trimester	prospective cohort	exposed to other treatment, sick excluded	Adjustment: No	1.28 [0.61;2.70] ^C excluded (control group)	8/88 178/2,461	186	88		ref
S16183 R79508	The NAAED (Controls unexposed, disease free) (Indications NOS), 2025	Small for gestational age	at least 1st trimester	prospective cohort	unexposed, disease free	Adjustment: No	0.96 [0.45;2.03] ^C	8/88 124/1,311	132	88		ref
					Total	1 studies	0.96 [0.45;2.03]		132	88
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; ^C: calculated odds ratio from numbers of events and effectives

Forest plot

1: Controls unexposed, disease free) (Indications NOS;

Sensitivity analysis

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded 16193