Gabapentin (All indications) updated on 04-22-2025

Neonatal disorders (as a whole)

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S8517
R28091		 Coste (Controls unexposed, NOS) (Mixed indications), 2020 Neonatal condition during pregnancy (anytime or not specified) retrospective cohort (claims database) unexposed (general population or NOS) Adjustment: No 1.09 [0.82;1.46] C 53/378   222,201/1,710,441 222,254 378
ref
Total 1 studies 1.09 [0.82;1.46] 222,254 378
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Coste (Controls unexposed, NOS) (Mixed indications), 2020Coste, 2020 1 1.09[0.82; 1.46]222,2543780%ROB confusion: NAROB selection: NAROB classification: NAROB missing: NAROB mesure: NAROB reporting: NA0.55.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

1: Controls unexposed, NOS) (Mixed indications;

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 1.09[0.82; 1.46]222,254378 -NACoste (Controls unexposed, NOS) (Mixed indications), 2020 1 case control studiescase control studies 0 Type of controls unexposed (disease free or unspecified)unexposed (disease free or unspecified) 1.09[0.82; 1.46]222,254378 -NACoste (Controls unexposed, NOS) (Mixed indications), 2020 1 Tags Adjustment   - No  - No 1.09[0.82; 1.46]222,254378 -NACoste (Controls unexposed, NOS) (Mixed indications), 2020 1 All studiesAll studies 1.09[0.82; 1.46]222,254378 -NACoste (Controls unexposed, NOS) (Mixed indications), 2020 10.55.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 1.09[0.82; 1.46]222,254378 -NACoste (Controls unexposed, NOS) (Mixed indications), 2020 10.510.01.0