Phenobarbital (All indications) updated on 04-22-2025

Jaundice / Icterus

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S9101
R31198		 D'Souza (Phenobarbital) (Controls unexposed, disease free), 1991 Jaundice throughout pregnancy prospective cohort unexposed, disease free excluded Adjustment: No Matched 3.40 [0.14;85.28] C
excluded (control group) 		0/4   2/62 2 4
ref
S9102
R31227		 D'Souza (Phenobarbital) (Controls unexposed, sick), 1991 Jaundice throughout pregnancy prospective cohort unexposed, sick Adjustment: No 0.62 [0.02;19.59] C 0/4   1/8 1 4
ref
Total 1 studies 0.62 [0.02;19.59] 1 4
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF D'Souza (Phenobarbital) (Controls unexposed, sick), 1991D'Souza, 1991 1 0.62[0.02; 19.59]140%ROB confusion: NAROB selection: NAROB classification: NAROB missing: NAROB mesure: NAROB reporting: NA0.22.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

1: Phenobarbital) (Controls unexposed, sick;

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 0.62[0.02; 19.59]14 -NAD'Souza (Phenobarbital) (Controls unexposed, sick), 1991 1 case control studiescase control studies 0 Type of controls unexposed, sickunexposed, sick 0.62[0.02; 19.59]14 -NAD'Souza (Phenobarbital) (Controls unexposed, sick), 1991 1 Tags Adjustment   - No  - No 0.62[0.02; 19.59]14 -NAD'Souza (Phenobarbital) (Controls unexposed, sick), 1991 1 All studiesAll studies 0.62[0.02; 19.59]14 -NAD'Souza (Phenobarbital) (Controls unexposed, sick), 1991 10.210.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded 9101

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 3.40[0.14; 85.28]24 -NAD'Souza (Phenobarbital) (Controls unexposed, disease free), 1991 1 unexposed, sick controlsunexposed, sick controls 0.62[0.02; 19.59]14 -NAD'Souza (Phenobarbital) (Controls unexposed, sick), 1991 10.510.01.0