Phenobarbital (All indications) updated on 04-22-2025

Large head circumference for gestational age

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S9158
R31476		 Díaz-Romero (Phenobarbital), 1999 Head circumference >2 SD during pregnancy (anytime or not specified) cohort unexposed, sick Adjustment: No 5.00 [0.07;366.35] C 0/2   0/8 0 2
ref
Total 1 studies 5.00 [0.07;366.35] 0 2
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Díaz-Romero (Phenobarbital), 1999Díaz-Romero, 1999 1 5.00[0.07; 366.35]020%ROB confusion: NAROB selection: NAROB classification: NAROB missing: NAROB mesure: NAROB reporting: NA0.910.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

1: Phenobarbital;

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 5.00[0.07; 366.35]-2 -NADíaz-Romero (Phenobarbital), 1999 1 case control studiescase control studies 0 Type of controls unexposed, sickunexposed, sick 5.00[0.07; 366.35]-2 -NADíaz-Romero (Phenobarbital), 1999 1 Tags Adjustment   - No  - No 5.00[0.07; 366.35]-2 -NADíaz-Romero (Phenobarbital), 1999 1 All studiesAll studies 5.00[0.07; 366.35]-2 -NADíaz-Romero (Phenobarbital), 1999 10.510.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed, sick controlsunexposed, sick controls 5.00[0.07; 366.35]-2 -NADíaz-Romero (Phenobarbital), 1999 10.510.01.0