| id | Study | Lib. in paper | Exposition period | Study type  | 
                Control type  | 
                Tags | OR 95%CI | x1/n1 x0/n0 | no cases | no exposed | ROB | Ref. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| S9099 R31169  | 
                Burja (Phenobarbital) (Controls unexposed, disease free), 2006 | Feeding problems | during pregnancy (anytime or not specified) | retrospective cohort (registry) | unexposed, disease free excluded | Adjustment: No | 
                    27.13 [0.50;1462.54] C  excluded (control group)  | 
                
                0/1 7/211 | 7 | 1 | 
                    
                    
                         | 
                ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S9100 R31174  | 
                Burja (Phenobarbital) (Controls unexposed, sick), 2006 | Feeding problems | during pregnancy (anytime or not specified) | retrospective cohort (registry) | unexposed, sick | Adjustment: No | 20.33 [0.29;1423.95] C | 0/1 1/32 | 1 | 1 | 
                    
                    
                         | 
                ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S9154 R31468  | 
                Yerby (Phenobarbital), 1992 | Feeding difficulties | during pregnancy (anytime or not specified) | prospective cohort | unexposed, disease free | Adjustment: No | 5.00 [0.29;87.55] C | 1/10 1/46 | 2 | 10 | 
                    
                    
                         | 
                ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S9101 R31191  | 
                D'Souza (Phenobarbital) (Controls unexposed, disease free), 1991 | Feeding difficulty (tube fed) | throughout pregnancy | prospective cohort | unexposed, disease free excluded | Adjustment: No Matched | 
                    17.57 [0.30;1024.08] C  excluded (control group)  | 
                
                0/4 0/62 | 0 | 4 | 
                    
                    
                         | 
                ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S9102 R31220  | 
                D'Souza (Phenobarbital) (Controls unexposed, sick), 1991 | Feeding difficulty (tube fed) | throughout pregnancy | prospective cohort | unexposed, sick | Adjustment: No | 2.14 [0.03;131.94] C | 0/4 0/8 | 0 | 4 | 
                    
                    
                         | 
                ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Total | 3 studies | 5.62 [0.72;44.00] | 3 | 15 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1: Phenobarbital) (Controls unexposed, sick; 2: Phenobarbital; 3: Phenobarbital) (Controls unexposed, sick;
Funnel plot not drawn. Less than 3 points.
Asymetry test p-value = NaN (by Egger's regression)
not enought points
Funnel plot not drawn. Less than 3 points.
excluded 9101, 9099