Phenobarbital (All indications) updated on 04-22-2025

Late intrauterine deaths (> 22 weeks) / Stillbirths

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S9155
R31470		 Tomson (Phenobarbital), 2015 Stillbirths at least 1st trimester prospective cohort exposed to other treatment, sick Adjustment: No 2.46 [0.49;12.25] C 2/260   6/1,910 8 260
ref
Total 1 studies 2.46 [0.49;12.25] 8 260
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Tomson (Phenobarbital), 2015Tomson, 2015 1 2.46[0.49; 12.25]82600%ROB confusion: NAROB selection: NAROB classification: NAROB missing: NAROB mesure: NAROB reporting: NA0.95.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

1: Phenobarbital;

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 2.46[0.49; 12.25]8260 -NATomson (Phenobarbital), 2015 1 case control studiescase control studies 0 Type of controls exposed to other treatment, sickexposed to other treatment, sick 2.46[0.49; 12.25]8260 -NATomson (Phenobarbital), 2015 1 Tags Adjustment   - No  - No 2.46[0.49; 12.25]8260 -NATomson (Phenobarbital), 2015 1 All studiesAll studies 2.46[0.49; 12.25]8260 -NATomson (Phenobarbital), 2015 10.55.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls exposed to other treatment, sick controlsexposed to other treatment, sick controls 2.46[0.49; 12.25]8260 -NATomson (Phenobarbital), 2015 10.510.01.0