Triptans

Gastroschisis

R analysis
id Study   Lib. in paper Exposition period    Study type  Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S3556
R7070
Werler, 2009 Gastroschisis 1st trimester case control unexposed (general population or NOS) Adjustment: No 0.80 [0.10;6.38] C 1/9   513/3,782 514 9
ref
Total 1 studies 0.80 [0.10;6.38] 514 9
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Werler, 2009Werler, 2009 0.80[0.10; 6.38]51490%ROB confusion: NAROB selection: NAROB classification: NAROB missing: NAROB mesure: NAROB reporting: NA0.22.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 0 case control studiescase control studies 0.80[0.10; 6.38]5149 -NAWerler, 2009 1 Type of controls unexposed (disease free or unspecified)unexposed (disease free or unspecified) 0.80[0.10; 6.38]5149 -NAWerler, 2009 1 Tags Adjustment   - No  - No 0.80[0.10; 6.38]5149 -NAWerler, 2009 1 All studiesAll studies 0.80[0.10; 6.38]5149 -NAWerler, 2009 10.210.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 0.80[0.10; 6.38]5149 -NAWerler, 2009 10.510.01.0