Citalopram updated on 07-01-2025

Gastroschisis

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S7487
R22409		 Given, 2017 Gastroschisis (excluding diabetes and anti-epileptic medication exposed) 1st trimester case control unexposed (general population or NOS) Adjustment: Yes Monotherapy: no or not specified 3.11 [1.25;7.74] 5/136   -/- - 136
ref
Total 1 studies 3.11 [1.25;7.74] 0 136
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Given, 2017Given, 2017 3.11[1.25; 7.74]-1360%ROB confusion: NAROB selection: NAROB classification: NAROB missing: NAROB mesure: NAROB reporting: NA0.910.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 0 case control studiescase control studies 3.11[1.25; 7.74]-136 -NAGiven, 2017 1 Type of controls unexposed (disease free or unspecified)unexposed (disease free or unspecified) 3.11[1.25; 7.74]-136 -NAGiven, 2017 1 Tags Adjustment   - Yes  - Yes 3.11[1.25; 7.74]-136 -NAGiven, 2017 1 Monotherapy   - no or not specified  - no or not specified 3.11[1.25; 7.74]-136 -NAGiven, 2017 1 All studiesAll studies 3.11[1.25; 7.74]-136 -NAGiven, 2017 10.510.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 3.11[1.25; 7.74]-136 -NAGiven, 2017 10.510.01.0