Citalopram updated on 07-01-2025

Therapeutic terminations of pregnancy

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S6415
R17604		 Sivojelezova (Control exposed to other SSRI), 2005 Therapeutic abortions during pregnancy (anytime or not specified) prospective cohort exposed to other treatment, sick excluded Adjustment: No Matched Monotherapy: no or not specified 2.02 [0.18;22.50] C
excluded (control group) 		2/132   1/132 3 132
ref
S6414
R17596		 Sivojelezova (Control unexposed, NOS), 2005 Therapeutic abortions during pregnancy (anytime or not specified) prospective cohort unexposed (general population or NOS) Adjustment: No Matched Monotherapy: no or not specified 5.08 [0.24;106.79] C 2/132   0/132 2 132
ref
Total 1 studies 5.08 [0.24;106.79] 2 132
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Sivojelezova (Control unexposed, NOS), 2005Sivojelezova, 2005 1 5.08[0.24; 106.79]21320%ROB confusion: criticalROB selection: moderateROB classification: moderateROB missing: unclearROB mesure: moderateROB reporting: moderate0.920.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

1: Control unexposed, NOS;

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 5.08[0.24; 106.79]2132 -NASivojelezova (Control unexposed, NOS), 2005 1 case control studiescase control studies 0 Type of controls unexposed (disease free or unspecified)unexposed (disease free or unspecified) 5.08[0.24; 106.79]2132 -NASivojelezova (Control unexposed, NOS), 2005 1 Tags Adjustment   - No  - No 5.08[0.24; 106.79]2132 -NASivojelezova (Control unexposed, NOS), 2005 1 MatchedMatched 5.08[0.24; 106.79]2132 -NASivojelezova (Control unexposed, NOS), 2005 1 Monotherapy   - no or not specified  - no or not specified 5.08[0.24; 106.79]2132 -NASivojelezova (Control unexposed, NOS), 2005 1 All studiesAll studies 5.08[0.24; 106.79]2132 -NASivojelezova (Control unexposed, NOS), 2005 10.520.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded 6415

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 5.08[0.24; 106.79]2132 -NASivojelezova (Control unexposed, NOS), 2005 1 exposed to other treatment, sick controlsexposed to other treatment, sick controls 2.02[0.18; 22.50]3132 -NASivojelezova (Control exposed to other SSRI), 2005 10.510.01.0