Moclobemide updated on 07-01-2025

Early intrauterine deaths (< 22 weeks) / Spontaneous abortions

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S11842
R43458		 Yaris, 2005 Spontaneous abortions during pregnancy (anytime or not specified) prospective cohort unexposed (general population or NOS) Adjustment: No Monotherapy: no or not specified 4.43 [0.48;40.72] C 1/7   9/248 10 7
ref
Total 1 studies 4.43 [0.48;40.72] 10 7
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Yaris, 2005Yaris, 2005 4.43[0.48; 40.72]1070%ROB confusion: criticalROB selection: unclearROB classification: moderateROB missing: unclearROB mesure: unclearROB reporting: moderate0.910.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 4.43[0.48; 40.72]107 -NAYaris, 2005 1 case control studiescase control studies 0 Type of controls unexposed (disease free or unspecified)unexposed (disease free or unspecified) 4.43[0.48; 40.72]107 -NAYaris, 2005 1 Tags Adjustment   - No  - No 4.43[0.48; 40.72]107 -NAYaris, 2005 1 Monotherapy   - no or not specified  - no or not specified 4.43[0.48; 40.72]107 -NAYaris, 2005 1 All studiesAll studies 4.43[0.48; 40.72]107 -NAYaris, 2005 10.510.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 4.43[0.48; 40.72]107 -NAYaris, 2005 10.510.01.0