Trazodone updated on 07-01-2025

Postpartum hemorrhage

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S11739
R43095		 Palmsten b, 2013 Postpartum hemorrhage (ICD-9 code for 666.x) late pregnancy retrospective cohort (claims database) unexposed, sick Adjustment: Yes Monotherapy: substance alone among all Antidep (SSRI, SNRI, ...) Unexposed sick: old history of illness/treatment (> 12 months before pregnancy) or not specified 1.85 [0.90;3.80] -/139   1,896/69,044 - 139
ref
Total 1 studies 1.85 [0.90;3.80] 0 139
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Palmsten b, 2013Palmsten b, 2013 1.85[0.90; 3.80]-1390%ROB confusion: seriousROB selection: lowROB classification: criticalROB missing: unclearROB mesure: moderateROB reporting: moderate0.55.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 1.85[0.90; 3.80]-139 -NAPalmsten b, 2013 1 case control studiescase control studies 0 Type of controls unexposed, sickunexposed, sick 1.85[0.90; 3.80]-139 -NAPalmsten b, 2013 1 Tags Adjustment   - Yes  - Yes 1.85[0.90; 3.80]-139 -NAPalmsten b, 2013 1 Monotherapy   - substance alone among all Antidep ( ...  - substance alone among all Antidep (SSRI, SNRI, ...) 1.85[0.90; 3.80]-139 -NAPalmsten b, 2013 1 Unexposed sick   - old history of illness/treatment (> ...  - old history of illness/treatment (> 12 months before pregnancy) or not specified 1.85[0.90; 3.80]-139 -NAPalmsten b, 2013 1 All studiesAll studies 1.85[0.90; 3.80]-139 -NAPalmsten b, 2013 10.55.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed, sick controlsunexposed, sick controls 1.85[0.90; 3.80]1,887139 -NAPalmsten b, 2013 10.510.01.0