Oxprenolol (versus unexposed) updated on 12-17-2024

Caesarean

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S14283
R56187		 Fidler, 1983 Elective caesarean section during pregnancy (anytime or not specified) prospective cohort unexposed, disease free Adjustment: No Indications Antihypertensive: All hypertensions, any indications or not specified Matched 1.52 [0.64;3.62] C 11/50   15/96 26 50
ref
Total 1 studies 1.52 [0.64;3.62] 26 50
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Fidler, 1983Fidler, 1983 1.52[0.64; 3.62]26500%ROB confusion: seriousROB selection: lowROB classification: moderateROB missing: lowROB mesure: moderateROB reporting: moderate0.55.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 1.52[0.64; 3.62]2650 -NAFidler, 1983 1 case control studiescase control studies 0 Type of controls unexposed (disease free or unspecified)unexposed (disease free or unspecified) 1.52[0.64; 3.62]2650 -NAFidler, 1983 1 Tags Adjustment   - No  - No 1.52[0.64; 3.62]2650 -NAFidler, 1983 1 Indications Antihypertensive   - All hypertensions, any indications ...  - All hypertensions, any indications or not specified 1.52[0.64; 3.62]2650 -NAFidler, 1983 1 MatchedMatched 1.52[0.64; 3.62]2650 -NAFidler, 1983 1 All studiesAll studies 1.52[0.64; 3.62]2650 -NAFidler, 1983 10.55.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 1.52[0.64; 3.62]2650 -NAFidler, 1983 10.510.01.0

Umbrella review (other published meta-analyses)

Published MAControlPeriodTE95% CIn exposedkI2 Bellos (Cesarean delivery (Randomized control ...Bellos (Cesarean delivery (Randomized controlled trial and Cohort studies)) 0.55[0.15; 1.99]NA-U,Sunexposed, sickAnyduring pregnancy (anytime or not specified)studies TTT-9 Bellos (Cesarean delivery (Randomized control ...Bellos (Cesarean delivery (Randomized controlled trial only)) 0.55[0.15; 1.99]NA-U,Sunexposed, sickAnyduring pregnancy (anytime or not specified)studies TTT-9 metaPregmetaPreg 1.52[0.64; 3.62]NaN%50----Fidler, 1983 10.510.01.0