Carteolol (versus unexposed) updated on 12-17-2024

Low birth weight (< 2500g)

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S14243
R55946		 Ishibashi, 2017 Low birthweight infants (birth weight less than 2500 kg) during pregnancy (anytime or not specified) retrospective cohort unexposed, sick Adjustment: No Indications Antihypertensive: Only cardiac indications other than hypertension (long QT syndrome, structural heart disease, ...) 1.67 [0.06;42.98] C 0/2   14/87 14 2
ref
Total 1 studies 1.67 [0.06;42.98] 14 2
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Ishibashi, 2017Ishibashi, 2017 1.67[0.06; 42.98]1420%ROB confusion: criticalROB selection: criticalROB classification: criticalROB missing: unclearROB mesure: moderateROB reporting: low0.55.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 1.67[0.06; 42.98]142 -NAIshibashi, 2017 1 case control studiescase control studies 0 Type of controls unexposed, sickunexposed, sick 1.67[0.06; 42.98]142 -NAIshibashi, 2017 1 Tags Adjustment   - No  - No 1.67[0.06; 42.98]142 -NAIshibashi, 2017 1 Indications Antihypertensive   - Only cardiac indications other than ...  - Only cardiac indications other than hypertension (long QT syndrome, structural heart disease, ...) 1.67[0.06; 42.98]142 -NAIshibashi, 2017 1 All studiesAll studies 1.67[0.06; 42.98]142 -NAIshibashi, 2017 10.55.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed, sick controlsunexposed, sick controls 1.67[0.06; 42.98]142 -NAIshibashi, 2017 10.510.01.0