Propranolol (versus unexposed) updated on 12-17-2024

Late intrauterine deaths (> 22 weeks)

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S14296
R56319		 Lieberman, 1978 Stillbirth during pregnancy (anytime or not specified) retrospective cohort unexposed, sick Adjustment: No Indications Antihypertensive: All hypertensions, any indications or not specified 14.00 [1.86;105.27] C 7/9   3/15 10 9
ref
Total 1 studies 14.00 [1.86;105.27] 10 9
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Lieberman, 1978Lieberman, 1978 14.00[1.86; 105.27]1090%ROB confusion: criticalROB selection: unclearROB classification: unclearROB missing: lowROB mesure: unclearROB reporting: moderate0.950.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 14.00[1.86; 105.27]109 -NALieberman, 1978 1 case control studiescase control studies 0 Type of controls unexposed, sickunexposed, sick 14.00[1.86; 105.27]109 -NALieberman, 1978 1 Tags Adjustment   - No  - No 14.00[1.86; 105.27]109 -NALieberman, 1978 1 Indications Antihypertensive   - All hypertensions, any indications ...  - All hypertensions, any indications or not specified 14.00[1.86; 105.27]109 -NALieberman, 1978 1 All studiesAll studies 14.00[1.86; 105.27]109 -NALieberman, 1978 10.550.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed, sick controlsunexposed, sick controls Out of scale14.00[1.86; 105.27]109 -NALieberman, 1978 10.510.01.0