Antithyroid drugs

Study Reference
Andersen, 2019

Andersen Maternal thyroid function, use of antithyroid drugs in early pregnancy and birth defects. J. Clin. Endocrinol. Metab. 2019; :

Andersen 2014 (MMI only), 2014

Andersen Antithyroid drugs and congenital heart defects: ventricular septal defect is part of the methimazole/carbimazole embryopathy. Eur J Endocrinol. 2014 Nov;171(5):C1-3. doi: 10.1530/EJE-14-0524. Epub 2014 Jul 28.

Andersen 2017 (control unexposed, disease free), 2017

Andersen Birth defects after use of antithyroid drugs in early pregnancy: a Swedish nationwide study. Eur. J. Endocrinol. 2017; 177:369-378

Andersen 2017 (control unexposed, sick), 2017

Andersen Birth defects after use of antithyroid drugs in early pregnancy: a Swedish nationwide study. Eur. J. Endocrinol. 2017; 177:369-378

Azizi (MMI only), 2002

Azizi Thyroid function and intellectual development of children of mothers taking methimazole during pregnancy J Endocrinol Invest. 2002;25(7):586-9.

Banhidy, 2011

Banhidy Possible association between hyperthyroidism in pregnant women and obstructive congenital abnormalities of urinary tract in their offspring--a population-based case-control study. J. Matern. Fetal. Neonatal. Med. 2011; 24:305-12

Barbero (MMI only), 2008

Barbero Choanal atresia associated with maternal hyperthyroidism treated with methimazole: a case-control study. Am. J. Med. Genet. A 2008; 146A:2390-5

Besancon, 2014

Besancon Management of neonates born to women with Graves' disease: a cohort study. Eur. J. Endocrinol. 2014; 170:855-62

Chen (control unexposed, disease free), 2011

Chen Risk of adverse perinatal outcomes with antithyroid treatment during pregnancy: a nationwide population-based study. BJOG 2011; 118:1365-73

Chen (control unexposed, sick), 2011

Chen Risk of adverse perinatal outcomes with antithyroid treatment during pregnancy: a nationwide population-based study. BJOG 2011; 118:1365-73

Clementi, 2010

Clementi Treatment of hyperthyroidism in pregnancy and birth defects. J. Clin. Endocrinol. Metab. 2010; 95:E337-41

Davis (PTU only), 1989

Davis Thyrotoxicosis complicating pregnancy. Am. J. Obstet. Gynecol. 1989; 160:63-70

Di Gianantonio (MMI only), 2001

Di Gianantonio Adverse effects of prenatal methimazole exposure. Teratology 2001; 64:262-6

Gianetti, 2015

Gianetti Pregnancy outcome in women treated with methimazole or propylthiouracil during pregnancy. J. Endocrinol. Invest. 2015; 38:977-85

Howley, 2017

Howley Thyroid Medication Use and Birth Defects in the National Birth Defects Prevention Study. Birth Defects Res 2017; 109:1471-1481

Khoury (MMI only), 1989

Khoury Maternal thyroid disease and risk of birth defects in offspring: a population-based case-control study. Paediatr Perinat Epidemiol 1989; 3:402-20

Korelitz (control unexposed, disease free), 2013

Korelitz Prevalence of thyrotoxicosis, antithyroid medication use, and complications among pregnant women in the United States. Thyroid 2013; 23:758-65

Korelitz (control unexposed, sick), 2013

Korelitz Prevalence of thyrotoxicosis, antithyroid medication use, and complications among pregnant women in the United States. Thyroid 2013; 23:758-65

Lo (control unexposed, disease free), 2015

Lo Gestational thyrotoxicosis, antithyroid drug use and neonatal outcomes within an integrated healthcare delivery system. Thyroid 2015; 25:698-705

Lo (control unexposed, sick), 2015

Lo Gestational thyrotoxicosis, antithyroid drug use and neonatal outcomes within an integrated healthcare delivery system. Thyroid 2015; 25:698-705

McCarroll (Buckinghamshire control group) (MMI only), 1976

McCarroll Long-term assessment of children exposed in utero to carbimazole. Arch. Dis. Child. 1976; 51:532-6

McCarroll (Northern Ireland control group) (MMI only), 1976

McCarroll Long-term assessment of children exposed in utero to carbimazole. Arch. Dis. Child. 1976; 51:532-6

Mitsuda, 1992

Mitsuda Risk factors for developmental disorders in infants born to women with Graves disease. Obstet Gynecol 1992; 80:359-64

Momotani, 1997

Momotani Effects of propylthiouracil and methimazole on fetal thyroid status in mothers with Graves' hyperthyroidism. J. Clin. Endocrinol. Metab. 1997; 82:3633-6

Momotani, 1977

Momotani [Management of patients with thyrotoxicosis of childbearing age (author's transl)]. Nihon Naibunpi Gakkai Zasshi 1977; 53:1148-58

Momotani (MMI only), 1984

Momotani Maternal hyperthyroidism and congenital malformation in the offspring. Clin Endocrinol (Oxf). 1984;20(6):695-700.

Phoojaroenchanachai, 2001

Phoojaroenchanachai Effect of maternal hyperthyroidism during late pregnancy on the risk of neonatal low birth weight. Clin. Endocrinol. (Oxf) 2001; 54:365-70

Rosenfeld (PTU only), 2009

Rosenfeld Pregnancy outcome, thyroid dysfunction and fetal goitre after in utero exposure to propylthiouracil: a controlled cohort study. Br J Clin Pharmacol 2009; 68:609-17

Schurmann, 2016

Schurmann Pregnancy outcomes after fetal exposure to antithyroid medications or levothyroxine. Early Hum. Dev. 2016; 101:73-7

Seo, 2018

Seo Antithyroid Drugs and Congenital Malformations: A Nationwide Korean Cohort Study. Ann. Intern. Med. 2018; 168:405-413

Stice, 1984

Stice The management of Graves' disease during pregnancy. Surg Gynecol Obstet 1984; 158:157-60

Wing, 1994

Wing A comparison of propylthiouracil versus methimazole in the treatment of hyperthyroidism in pregnancy. Am. J. Obstet. Gynecol. 1994; 170:90-5

Yoshihara, 2021

Yoshihara Exposure to Propylthiouracil in the First Trimester of Pregnancy and Birth Defects: A Study at a Single Institution. J Endocr Soc 2021; 5:bvaa204

Yoshihara, 2012

Yoshihara Treatment of graves' disease with antithyroid drugs in the first trimester of pregnancy and the prevalence of congenital malformation. J. Clin. Endocrinol. Metab. 2012; 97:2396-403

Zhang (PTU only), 2016

Zhang Follow-up and evaluation of the pregnancy outcome in women of reproductive age with Graves' disease after 131Iodine treatment. J. Radiat. Res. 2016; 57:702-708