potential COVID-19 treatments living meta-analysis of clinical studies

demonstrated suggested inconclusive safety concern ongoing study display ongoing demontrated benefit only observational study

	COVID-19 prophylaxis (children)
potential COVID-19 treatments
vaccines
mRNA vaccine
Comirnaty (tozinameran - Pfizer/BIONTECH)	C4591001 ... Glatman-Freedman A Olson ... Walter E.B. ... Olson ... June Reis Veneti Klein ... Tartof Lutrick ... Price
Spikevax (Moderna mRNA-1273 COVID-19 vaccine)	teenCOVE ... kidCOVE ...
protein subunit vaccine
Nuvaxovid (NVX-CoV2373) Novavax	PREVENT-19 adolescents

5347	Mehra, 2020	2	12	4	excluded	not a RCT	high risk of bias
5521	Del Amo, 2020	2	0	0	excluded		risk of bias not avaialble
7070	PHE variants (Technical briefing 12 22 may 2021), 2021	2	20	2	excluded	not a RCT
7420	PHE (Stowe), 2021	2	13	3	excluded	not a RCT	high risk of bias
8149	PHE Technical briefing 16 (11/18 June 2021), 2021	2	13	3	excluded	not a RCT	high risk of bias
8275	Musser, 2021	2	13	0	excluded	not a RCT	risk of bias not avaialble
8350	Rosenberg, 2021	2	13	0	excluded	not a RCT	risk of bias not avaialble
8515	Scobie, 2021	2	20	0	excluded	not a RCT	risk of bias not avaialble
9170	UKHSA report 33 (23 december 2021), 2021	2	20	0	excluded	not a RCT	risk of bias not avaialble
9176	UKHSA 31 december 2021, 2021	2	20	0	excluded	not a RCT	risk of bias not avaialble
9214	Southern California (Lewnard), 2022	2	13	0	excluded	not a RCT	risk of bias not avaialble
9294	UKHSA (report W4- 27 January), 2022	2	12	0	excluded	not a RCT	risk of bias not avaialble