table network network 2
demonstrated suggested inconclusive safety concern ongoing study display ongoing demontrated benefit only
COVID 19 outpatients
potential COVID-19 treatments
anti-inflammatoty and immuno-therapy
anti-inflammatory therapies
colchicine PRINCIPLE ... COLCORONA
corticosteroids
ciclesonide Clemency Ezer N ...
Immunostimulants drugs
convalescent plasma treatment CONV-ERT C3PO CoV-Early ...
Early convalescent plasma. CoV-Early ...
interferon
peginterferon Feld
neutralizing antibody
bamlanivimab monotherapy BLAZE-1 phase 2 ...
bamlanivimab/etesevimab BLAZE-1 phase 2 ... BLAZE-1 phase 3 ...
casirivimab/imdevimab (Ronapreve) Cov-2067 Weinreich ... Cov-2069 ...
sotrovimab (Xevudy; VIR-7831) COMET-ICE
inhaled corticosteroids
budesonide PRINCIPLE
antiviral and associated therapy
azithromycin ACTION PRINCIPLE Hinks ...
chloroquine and derivatives ALBERTA HOPE-Covid19
hydroxychloroquine COPE – Coalition V COVID-PEP Severity ... BCN PEP-CoV-2-Study 2 ... PATCH Cohort 1 ... Reis ...
fluvoxamine COVID-OUT ... Lenze ... TOGETHER ACTIV-6
hydroxychloroquine plus macrolides
azithromycin plus hydroxychloroquine Rodrigues Q-PROTECT ...
ivermectin ACTIV-6 ... IVERCORCOVID19 ... Chaccour ACTIV 6 ivermectin Buonfrate ... COVID-OUT ... Lopez-Medina TOGETHER ...
lopinavir/ritonavir Reis ...
molnupiravir MOVe-OUT Fischer ...
nirmatrelvir / ritonavir (Paxlovid) EPIC-HR
remdesivir PINETREE ...
sofosbuvir and daclatasvir Roozbeh
Oral antidiabetic drugs
metformin COVID-OUT ...
Renin-angiotensin-system-acting agents
angiotensin receptor blockers (ARBs) University of Minnesota
discontinuation of ACEI/ARB ACEI-COVID ...
Vitamins
vitamin C Thomas ...
zinc plus vitamin c Thomas ...

74 studies excluded by filtering options 0

4909 Lee, 2004 010selection pending
4910 Soo, 2004 000selection pending
4911 HKU/UCH SARS Study Group, 2004 000selection pending
4912 Chan, 2003 000selection pending
4913 Beigel, 2018 010selection pending
5092 Yang, 2020 1133not a RCThigh risk of bias
5228 Bean, 2020 1193not a RCThigh risk of bias
5295 Zhang, 2020 1133not a RCThigh risk of bias
5331 Li, 2020 1134not a RCThigh risk of bias
5332 Meng, 2020 1134not a RCThigh risk of bias
5345 Yan et al., 2020 1204not a RCThigh risk of bias
5346 Mancia, 2020 1203not a RCThigh risk of bias
5347 Mehra, 2020 2124excludednot a RCThigh risk of bias
5348 Reynolds (COVID positive patient), 2020 1133not a RCThigh risk of bias
5349 Reynolds (prophylaxis), 2020 1133not a RCThigh risk of bias
5370 Khera (outpatients), 2020 1133not a RCThigh risk of bias
5372 Khera (inpatients), 2020 1133not a RCThigh risk of bias
5399 Northwell Consortium (Richardson), 2020 0990selection pending
5440 Morales, 2020 1130not a RCTrisk of bias not avaialble
5442 Mancia, 2020 000selection pending
5521 Del Amo, 2020 200excludedrisk of bias not avaialble
5532 Fosbøl, 2020 000selection pending
5604 Schneeweiss, 0 0130selection pending
5605 Vila-Corcole, 0 0130selection pending
5619 Pan, 2020 0130selection pending
5629 Fosbol, 2020 000selection pending
5797 Rossi, 0 0130selection pending
5903 Anzola, 2020 0100selection pending
6660 Bae, 2021 0120selection pending
6729 Shah, 2021 1133not a RCThigh risk of bias
6788 Waissengrin, 2021 0130selection pending
6790 Pawlowski, 2021 1130not a RCTrisk of bias not avaialble
6857 Anderson, 2020 000selection pending
6894 Andrejko, 2021 1200not a RCTrisk of bias not avaialble
6927 Rossman, 2021 0130selection pending
6931 Yair, 2921 1320not a RCTrisk of bias not avaialble
6934 Boyarsky, 2021 1320not a RCTrisk of bias not avaialble
6949 Pawlowski, 2021 1130not a RCTrisk of bias not avaialble
6981 Public Health England (Harris), 2021 1133not a RCThigh risk of bias
7025 Haberman, 2021 0130selection pending
7055 Shroff, 2021 000selection pending
7070 PHE variants (Technical briefing 12 22 may 2021), 2021 2202excludednot a RCT
7325 Skowronski, 2021 0130selection pending
7419 Scotland delta (Sheikh), 2021 1203not a RCThigh risk of bias
7420 PHE (Stowe), 2021 2133excludednot a RCThigh risk of bias
7940 Wall, 2021 000selection pending
7950 Harris, 2021 1133not a RCThigh risk of bias
8143 Butt, 2021 1202not a RCT
8147 Canada (Nasreen), 2021 1202not a RCT
8149 PHE Technical briefing 16 (11/18 June 2021), 2021 2133excludednot a RCThigh risk of bias
8150 Ramasamy, 2021 0320selection pending
8163 Israel delta press release, 0 100risk of bias not avaialble
8164 Public Health England, May 16, 2021 (Bernal), 2021 1202not a RCT
8255 REACT-SCOT, 2021 1200not a RCTrisk of bias not avaialble
8272 Martinez-Baz, 2021 1130not a RCTrisk of bias not avaialble
8274 REACT-1 round 13 final report (Elliott, Imperial College London), 2021 1133not a RCThigh risk of bias
8275 Musser, 2021 2130excludednot a RCTrisk of bias not avaialble
8294 CDC Mesa County, Colorado, 2021 1133not a RCThigh risk of bias
8313 Bahl (Fully vaccinated vs unvaccinated), 2021 0100selection pending
8350 Rosenberg, 2021 2130excludednot a RCTrisk of bias not avaialble
8359 Oxford (Pouwels), 2021 1132not a RCT
8360 HEROES-RECOVER (Fowlkes), 2021 1133not a RCThigh risk of bias
8513 Grannis, 2021 1203not a RCThigh risk of bias
8514 VA (Bajema), 2021 1203not a RCThigh risk of bias
8515 Scobie, 2021 2200excludednot a RCTrisk of bias not avaialble
9170 UKHSA report 33 (23 december 2021), 2021 2200excludednot a RCTrisk of bias not avaialble
9176 UKHSA 31 december 2021, 2021 2200excludednot a RCTrisk of bias not avaialble
9214 Southern California (Lewnard), 2022 2130excludednot a RCTrisk of bias not avaialble
9216 Sultan, 2022 0120selection pending
9224 Reynolds, 2022 000selection pending
9267 Ostropolets, 2021 0120selection pending
9294 UKHSA (report W4- 27 January), 2022 2120excludednot a RCTrisk of bias not avaialble
9491 Li X, 2022 1120not a RCTrisk of bias not avaialble
9590 UKHSA report week 12 (24 March 2022), 2022 1120not a RCTrisk of bias not avaialble

 

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