table network network 2
demonstrated suggested inconclusive safety concern ongoing study display ongoing demontrated benefit only observational study
COVID 19 outpatients
antiviral and associated therapy
azithromycin Hinks ... PRINCIPLE Espitia-Hernandez ACTION
chloroquine and derivatives ALBERTA HOPE-Covid19
hydroxychloroquine COVID-PEP Severity ... Q-PROTECT -HCQ alone Agusti BCN PEP-CoV-2-Study 2 ... COMIHY Reis ... NCT04597775 PATCH Cohort 1 ... COPE – Coalition V
fluvoxamine COVID-OUT ... TOGETHER ACTIV-6 Lenze ...
hydroxychloroquine plus macrolides NCT04621461
azithromycin plus hydroxychloroquine Q-PROTECT ... Q-PROTECT -AZI ... Rodrigues
ivermectin ACTIV-6 ... Podder Chahla Chaccour TOGETHER ... Buonfrate ... IVERCORCOVID19 ... Lopez-Medina Espitia-Hernandez ACTIV 6 ivermectin COVID-OUT ...
ivermectin plus doxycycline Chowdhury A
lopinavir/ritonavir Reis ...
molnupiravir Fischer ... MOVe-OUT
nirmatrelvir / ritonavir (Paxlovid) EPIC-HR
nitazoxanide RM08-3008 ...
remdesivir PINETREE ...
sofosbuvir and daclatasvir Roozbeh
umifenovir (arbidol) Ramachandran
zinc Thomas ...

39 studies excluded by filtering options 2

4899 ChiCTR2000029826 (Cancelled by the investigator), 0 210excludedrisk of bias not avaialble
4905 ChiCTR2000029975, 0 2300excludednot a RCTrisk of bias not avaialble
4987 CloroCOVID19, 2020 213excludedhigh risk of bias
5209 SIMPLE (Grein), 0 2300excludednot a RCTrisk of bias not avaialble
5210 Ye et al., 2020 2990excludednot a RCTrisk of bias not avaialble
5226 Duke university (Hydroxychloroquine), 2020 210excludedrisk of bias not avaialble
5259 Duke University azithromycin, 2020 210excludedrisk of bias not avaialble
5288 Barbosa, 2020 2130excludednot a RCTrisk of bias not avaialble
5300 Raquel, 2019 210excludedrisk of bias not avaialble
5303 Jacobson, 2016 210excludedrisk of bias not avaialble
5308 Sperber, 1995 210excludedrisk of bias not avaialble
5309 Paton, 2012 210excludedrisk of bias not avaialble
5351 Mallat, 2020 2130excludednot a RCTrisk of bias not avaialble
5374 Million, 2020 2300excludednot a RCTrisk of bias not avaialble
5375 Mehra, 2020 2133excludednot a RCThigh risk of bias
5375 Mehra, 2020 2133excludednot a RCThigh risk of bias
5416 Guerin, 2020 2314excludednot a RCThigh risk of bias
5416 Guerin, 2020 2314excludednot a RCThigh risk of bias
5521 Del Amo, 2020 200excludedrisk of bias not avaialble
6080 IDEA, 2020 2100excludednot a RCTrisk of bias not avaialble
6083 IFORS (Pott-Junior), 2020 213excludedhigh risk of bias
6096 Elgazzar - treatment, 2020 213excludedhigh risk of bias
6097 Elgazzar - prophylaxis, 2020 213excludedhigh risk of bias
6098 Patel, 2020 2100excludednot a RCTrisk of bias not avaialble
6134 Morgenstern, 2020 2300excludednot a RCTrisk of bias not avaialble
6184 Erdem, 2020 2110excludednot a RCTrisk of bias not avaialble
6262 Yamamura, 2020 2300excludednot a RCTrisk of bias not avaialble
6267 Murohashi, 2020 2100excludednot a RCTrisk of bias not avaialble
6339 Delliere, 2020 2130excludednot a RCTrisk of bias not avaialble
6368 Niaee (vs placebo), 2020 213excludedhigh risk of bias
6374 NCT04425850 (Caravallo), 2020 2310excludednot a RCTrisk of bias not avaialble
6375 Cadegiani -Iver, 2020 2990excludednot a RCTrisk of bias not avaialble
6379 Chamie-Quintero,, 2020 2150excludednot a RCTrisk of bias not avaialble
6526 Dabbous, 2021 213excludedhigh risk of bias
6625 Nasir, 2020 2310excludednot a RCTrisk of bias not avaialble
6625 Nasir, 2020 2310excludednot a RCTrisk of bias not avaialble
7314 Samaha, 2021 213excludedhigh risk of bias
7995 Hazan, 2021 2320excludednot a RCTrisk of bias not avaialble
10322 Elgazzar, 0 200excludedrisk of bias not avaialble

 

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