Renin-angiotensin-system-acting agents living meta-analysis of clinical studies

demonstrated suggested inconclusive safety concern ongoing study display ongoing demontrated benefit only

	COVID 19 hospitalized
	COVID-19 mild to moderate
Renin-angiotensin-system-acting agents
discontinuation of ACEI/ARB	Lopes ...

5092	Yang, 2020	1	13	3		not a RCT	high risk of bias
5228	Bean, 2020	1	19	3		not a RCT	high risk of bias
5295	Zhang, 2020	1	13	3		not a RCT	high risk of bias
5331	Li, 2020	1	13	4		not a RCT	high risk of bias
5332	Meng, 2020	1	13	4		not a RCT	high risk of bias
5345	Yan et al., 2020	1	20	4		not a RCT	high risk of bias
5346	Mancia, 2020	1	20	3		not a RCT	high risk of bias
5347	Mehra, 2020	2	12	4	excluded	not a RCT	high risk of bias
5348	Reynolds (COVID positive patient), 2020	1	13	3		not a RCT	high risk of bias
5349	Reynolds (prophylaxis), 2020	1	13	3		not a RCT	high risk of bias
5370	Khera (outpatients), 2020	1	13	3		not a RCT	high risk of bias
5372	Khera (inpatients), 2020	1	13	3		not a RCT	high risk of bias
5376	Rhee, 2020	0	13	0	selection pending
5399	Northwell Consortium (Richardson), 2020	0	99	0	selection pending
5440	Morales, 2020	1	13	0		not a RCT	risk of bias not avaialble
5473	Huh, 2020	0	20	0	selection pending
5604	Schneeweiss, 0	0	13	0	selection pending
5605	Vila-Corcole, 0	0	13	0	selection pending
5619	Pan, 2020	0	13	0	selection pending
5651	Bravi, 2020	0	12	0	selection pending
5651	Bravi, 2020	0	12	0	selection pending
5797	Rossi, 0	0	13	0	selection pending
5903	Anzola, 2020	0	10	0	selection pending
5903	Anzola, 2020	0	10	0	selection pending
5903	Anzola, 2020	0	10	0	selection pending
6139	Dublin, 2020	0	12	0	selection pending
6139	Dublin, 2020	0	12	0	selection pending
6344	Christiansen, 2020	0	20	0	selection pending
6344	Christiansen, 2020	0	20	0	selection pending
6660	Bae, 2021	0	12	0	selection pending