| 4899 | ChiCTR2000029826 (Cancelled by the investigator), 0 | 2 | 1 | 0 | excluded | risk of bias not avaialble | |
| 4905 | ChiCTR2000029975, 0 | 2 | 30 | 0 | excluded | not a RCT | risk of bias not avaialble |
| 4987 | CloroCOVID19, 2020 | 2 | 1 | 3 | excluded | high risk of bias | |
| 5226 | Duke university (Hydroxychloroquine), 2020 | 2 | 1 | 0 | excluded | risk of bias not avaialble | |
| 5288 | Barbosa, 2020 | 2 | 13 | 0 | excluded | not a RCT | risk of bias not avaialble |
| 5300 | Raquel, 2019 | 2 | 1 | 0 | excluded | risk of bias not avaialble | |
| 5303 | Jacobson, 2016 | 2 | 1 | 0 | excluded | risk of bias not avaialble | |
| 5308 | Sperber, 1995 | 2 | 1 | 0 | excluded | risk of bias not avaialble | |
| 5309 | Paton, 2012 | 2 | 1 | 0 | excluded | risk of bias not avaialble | |
| 5351 | Mallat, 2020 | 2 | 13 | 0 | excluded | not a RCT | risk of bias not avaialble |
| 5374 | Million, 2020 | 2 | 30 | 0 | excluded | not a RCT | risk of bias not avaialble |
| 5375 | Mehra, 2020 | 2 | 13 | 3 | excluded | not a RCT | high risk of bias |
| 5416 | Guerin, 2020 | 2 | 31 | 4 | excluded | not a RCT | high risk of bias |
| 5560 | BCN PEP-CoV-2-Study 2 (Mitja Lancet-preprint), 2020 | 2 | 1 | 2 | excluded | ||
| 5564 | Kanran M, 2020 | 2 | 1 | 0 | excluded | risk of bias not avaialble | |
| 5776 | Alberici, 2020 | 2 | 13 | 4 | excluded | not a RCT | high risk of bias |
| 5864 | HYDRA, 2020 | 2 | 1 | 0 | excluded | risk of bias not avaialble | |
| 6032 | Mohana, 2020 | 2 | 12 | 0 | excluded | not a RCT | risk of bias not avaialble |
| 6697 | Thakar, 2021 | 2 | 1 | 0 | excluded | risk of bias not avaialble | |
| 6910 | Thakar, 2021 | 2 | 1 | 0 | excluded | risk of bias not avaialble |
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