table network network 2
demonstrated suggested inconclusive safety concern ongoing study display ongoing demontrated benefit only
COVID 19 hospitalized
COVID 19 hospitalizedCOVID 19 all comersCOVID-19 mild to moderateCOVID-19 severe or critically
anti-inflammatoty and immuno-therapy
anti-inflammatory therapies
anti GM-CSF
mavrilimumab MASH-COVID ...
clarithromycine Rashad ...
colchicine COLCOVID Salehzadeh GRECCO-19 RECOVERY ... Horby COL-COVID ...
Colchicine plus rosuvastatin Gaitan-Duarte ...
non-steroidal anti-inflammatory drugs
Indomethacin Ravichandran
stem cells Lanzoni Carmenate ... Shu Shi
corticosteroids
dexamethasone RECOVERY dexamethasone DEXA-COVID19 CODEX ... Jamaati
Dexamethasone 12mg COVID STEROID 2
Hydrocortisone CAPE-COVID Munch ...
methylprednisolone Tang X Metcovid Ranjbar Steroids-SARI
Immunostimulants drugs
convalescent plasma treatment ConCOVID ... ConPlas-19 COP-COVID-19 CONTAIN COVID-19 PC/COVID-19 NCT04397757 CONCOR-1 NCT04442191 DAWN-Plasma NCT04385199 COPLA-II trial NCT04403477 ... ASCOT RECOVERY ... CONFIDENT PERUCONPLASMA Bennett-Guerrero Salman Kirenga Co-CLARITY NCT04528368 Holm K CCAP-2 Baldeon Menichetti LIFESAVER Libster CP-COVID-19 Li Rasheed O’Donnell PlasmAr CAPSID AlQahtani REMAP-CAP ... RECOVER Pouladzadeh Sekine ...
Early convalescent plasma. Balcells
immunoglobulin therapy Sakoulas Tabarsi Raman
interferon
IFN beta-1a SOLIDARITY ... Darazam ... Kalil ...
high-dose IFN beta-1a Darazam
IFN beta-1b Rahmani Darazam ...
inhaled interferon
IFN alpha
pegylated interferon-α2b Pandit Shashi Bhushan
recombinant super-compound interferon rSIFN-co Li
SNG001 inhaled interferon beta Synairgen SG016
interferon / TFF2 Fu
peginterferon Jagannathan
PNB001 Lattmann
neutralizing antibody ITAC
amubarvimab/romlusevimab (BRII-196 and BRII-198-Brii Biosciences) ACTIV-3 ...
bamlanivimab monotherapy ACTIV-3/TICO LY-CoV555
casirivimab/imdevimab (Ronapreve) RECOVERY ... Somersan-Karakaya ...
cilgavimab and tixagevimab (Evusheld) ACTIV-3/TICO ...
equine polyclonal antibodies INM005 Lopardo
sotrovimab (Xevudy; VIR-7831) ACTIV-3/ TICO ...
Immunosuppressants drugs
adalimumab Fakharian
anakinra SAVE-MORE CORIMUNO-ANA-1
anti-interleukin-6
Levilimab V.Lomakin ...
sarilumab CORIMUNO-SARI-1 ... sarilumab Sanofi phase 3 outside US
sarilumab high dose (400mg) Lescure ...
sarilumab low dose (200mg) Lescure ...
tocilizumab Dongsheng Wang RCT-TCZ-COVID-19 EMPACTA RECOVERY Soin AS ... Rutgers NCT04412772 ... Declercq J ... NCT04577534 ... EU-CTR2020-001375-32 ... EU-CTR2020-001748-24 ... NCT04479358 ... NCT04434717 ... BACC Bay Tocilizumab Trial MARIPOSA COVACTA ... CORIMUNO-TOCI-1 ... REMAP-CAP ... Veiga Talaschian CORIMUNO-TOCI-ICU ... Rosas ...
canakinumab Sheng ... CAN-COVID
janus kinase (JAK) inhibitor
baricitinib COV-BARRIER ACTT-2 ... RECOVERY COV-BARRIER ...
ruxolitinib Cao
TD-0903
TD-0903 10mg Singh ...
TD-0903 1mg Singh ...
TD-0903 3mg Singh ...
tofacitinib STOP-COVID ...
lenzilumab LIVE-AIR ...
Kinase inhibitors
imatinib Aman
leflunomide Wang

31 studies excluded by filtering options 0

4930 Huijie Bian, 2020 2313excludednot a RCThigh risk of bias
5282 Hung, 2017 010selection pending
5317 Lu, 2020 1223not a RCThigh risk of bias
5319 Wu, 2020 1133not a RCThigh risk of bias
5422 Wang et al., 2020 010selection pending
5443 Victor, 2020 000selection pending
5453 Raef, 2020 1134not a RCThigh risk of bias
5454 Jianfeng, 2020 1133not a RCThigh risk of bias
5455 Tomasz, 2020 1204not a RCThigh risk of bias
5456 Fernández Cruz, 2020 1133not a RCThigh risk of bias
5472 GLUCOCOVID, 2020 113high risk of bias
5476 Yuan, 2020 0130selection pending
5484 Salton (Methylprednisolone), 2020 0134selection pending
5485 openSafely, 2020 0130selection pending
5510 Malgorzata, 2020 1134not a RCThigh risk of bias
5552 Rahman, 2020 0130selection pending
5568 Zhang, 2020 0130selection pending
5603 Albani, 2020 0130selection pending
5612 Bernaola, 2020 2130excludednot a RCTrisk of bias not avaialble
5614 Monreal, 2020 0130selection pending
5615 Nelson (Methylprednisolone), 2020 0130selection pending
5639 Li (Methylprednisolone, Shanghai cohort), 2020 0130selection pending
5796 SAM-COVID-19, 2020 0130selection pending
5840 Majmundar, 2020 0130selection pending
5939 Li (Methylprednisolone, Validation cohort), 2020 0130selection pending
5952 Rodriguez-Bano (intermediate-high dose CS), 2020 0130selection pending
5953 Rodriguez-Bano (CS pulse dose), 2020 0130selection pending
6036 Esba, 2020 0100selection pending
6046 Husain, 2020 010selection pending
6048 Wu, 2020 0110selection pending
8158 Yildiz, 2021 210excludedrisk of bias not avaialble

 

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