adjuvant therapies living meta-analysis of clinical studies

demonstrated suggested inconclusive safety concern ongoing study display ongoing demontrated benefit only

	COVID 19 hospitalized
	COVID 19 hospitalized	COVID-19 mild to moderate	COVID-19 severe or critically
adjuvant therapies
anticoagulant
anticoagulant, curative dose	COALIZAO ACTION	ATTACC, ACTIV-4a, and REMAP-CAP ...	COVID-PACT REMAP-CAP, ACTIV-4a, ATTACC ...
anticoagulation, intermediate prophylactic dose			INSPIRATION
heparin at therapeutic dose		RAPID ...

57 studies excluded by filtering options 0

5156	Teleman, 2004	2	20	0	excluded	not a RCT	risk of bias not avaialble
5157	Wu, 2004	2	20	0	excluded	not a RCT	risk of bias not avaialble
5158	Loeb, 2004	2	20	0	excluded	not a RCT	risk of bias not avaialble
5159	Wilder-Smith, 2005	2	20	0	excluded	not a RCT	risk of bias not avaialble
5160	Wang, 2020	2	20	0	excluded	not a RCT	risk of bias not avaialble
5161	Cowling, 2008	0	3	0	selection pending
5162	Cheng, 2010	2	20	0	excluded	not a RCT	risk of bias not avaialble
5163	MacIntyre, 2011	1	3	0			risk of bias not avaialble
5164	Jaeger, 2011	2	19	0	excluded	not a RCT	risk of bias not avaialble
5165	Aiello, 2012	1	3	0			risk of bias not avaialble
5166	Suess, 2012	1	3	0			risk of bias not avaialble
5167	Chokephaibulkit, 2012	2	20	0	excluded	not a RCT	risk of bias not avaialble
5168	Zhang, 2012	2	20	0	excluded	not a RCT	risk of bias not avaialble
5169	Sung, 2016	2	13	0	excluded	not a RCT	risk of bias not avaialble
5170	Zhang, 2017	2	20	0	excluded	not a RCT	risk of bias not avaialble
5171	Barasheed, 2014	1	1	0			risk of bias not avaialble
5172	Ma, 2004	2	20	0	excluded	not a RCT	risk of bias not avaialble
5173	Yin, 2004	2	20	0	excluded	not a RCT	risk of bias not avaialble
5174	A EFFACER, 2013	0	0	0	selection pending
5175	Cowling, 2009	1	1	0			risk of bias not avaialble
5176	Zhang, 2013	2	13	0	excluded	not a RCT	risk of bias not avaialble
5177	Nishiura, 2005	2	20	0	excluded	not a RCT	risk of bias not avaialble
5184	Aiello, 2010	1	3	0			risk of bias not avaialble
5185	Kim, 2012	0	0	0	selection pending
5186	Lau, 2004	0	0	0	selection pending
5187	Lau, 2004	0	0	0	selection pending
5188	Uchida, 2017	0	0	0	selection pending
5189	Wu, 2016	0	0	0	selection pending
5190	Canini, 2010	1	3	0			risk of bias not avaialble
5191	MacIntyre, 2009	1	1	0			risk of bias not avaialble
5192	MacIntyre, 2016	1	3	0			risk of bias not avaialble
5193	Simmerman, 2011	1	3	0			risk of bias not avaialble
5195	Al-Jasser, 2012	0	0	0	selection pending
5196	Balaban, 2012	0	0	0	selection pending
5197	Choudhry, 2006	0	0	0	selection pending
5198	Deris, 2010	0	0	0	selection pending
5199	Emamian, 2013	0	0	0	selection pending
5200	Gautret, 2009	0	0	0	selection pending
5201	Hashim, 2016	0	0	0	selection pending
5202	Zein, 2002	0	0	0	selection pending
5203	Shin, 2018	0	0	0	selection pending
5204	Alfelali, 2019	1	3	0			risk of bias not avaialble
5205	Jolie, 1998	0	0	0	selection pending
5206	Sung, 2012	0	0	0	selection pending
5207	Tahir, 2019	0	0	0	selection pending
5208	Larson, 2010	1	3	0			risk of bias not avaialble
5252	MacIntyre (medical mask), 2015	1	3	0			risk of bias not avaialble
5355	Paranjpe, 2020	1	13	4		not a RCT	high risk of bias
5441	Ayerbe, 2020	1	13	0		not a RCT	risk of bias not avaialble
5562	Davoodi, 2020	0	1	3	selection pending
5891	HEP-COVID, 2021	0	1	0	selection pending
5895	X-COVID-19, 2021	0	1	0	selection pending
5967	Gorenstein, 2020	0	0	0	selection pending
6283	Lynn, 2020	0	13	0	selection pending
6364	Denas, 2020	0	0	0	selection pending
6405	Li [retracted], 2020	2	0	0	excluded		risk of bias not avaialble
6448	Ménager, 2020	0	0	0	selection pending