Zinc and hydroxychloroquine.
Hydroxychloroquine at dose of 400 mg twice daily on the first day, then 200 mg twice daily for 5 days. Zinc in a dose of zinc sulfate 220 mg (50 mg of elemental zinc) twice daily.
Hydroxychloroquine only.
400 mg twice daily on the first day, then 200 mg twice daily for 5 days.
Both groups received the standard of care treatment for COVID-19 infection, according to the Egyptian Ministry of Health guidelines for 15 days.
COVID-19 (hospitalized or not)
All the included patients were classified into mild, moderate, severe, and critical according to the WHO case severity classification for COVID-19 infection.
Open-label
Multicenter, three major University hospitals in Cairo, Egypt.