id  Study  Lib. in paper  Exposition period  Study type 
Control type 
Tags  OR 95%CI  x1/n1 x0/n0  no cases  no exposed  ROB  Ref.  

S9299 R32356 
Dean (Valproate), 2002  Minor congenital malformations  at least 1st trimester  retrospective cohort  unexposed, sick  Adjustment: No  7.50 [2.49;22.56] ^{C}  25/47 5/38  30  47 

ref  
S9332 R32556 
Battino (Valproate), 1992  Minor anomalies  1st trimester  prospective cohort  unexposed, sick  Adjustment: No  7.62 [0.38;152.84] ^{C}  6/21 0/9  6  21 

ref  
S9352 R32721 
Robert (Valproate), 1986  Minor malformations  1st trimester  retrospective cohort  unexposed, sick  Adjustment: No  1.94 [0.38;9.97] ^{C}  3/15 4/35  7  15 

ref  
Total  3 studies  5.11 [2.13;12.25]  43  83  
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; ^{C:} calculated odds ratio from numbers of events and effectives 
1: Valproate; 2: Valproate; 3: Valproate;
Funnel plot not drawn. Less than 3 points.
Asymetry test pvalue = NaN (by Egger's regression)
not enought points
Funnel plot not drawn. Less than 3 points.
excluded