Lisinopril (versus unexposed)

Study	Country Study period Study design	Data source	Exposure definition	Non-exposure definition	Exposition period	Sample size (exposed/unexposed) Or (case / control)	Remarks	Risk of bias
Chintamaneni 2018	USA 2003 - 2014 retrospective cohort (claims database)	The Kaiser Permanente Southern California Region, USA.	Pregnant women exposed to Lisinopril during pregnancy.	unexposed (general population or NOS) Pregnant women not exposed to angiotensin-converting enzyme inhibitors (Ace-i) during pregnancy.	during pregnancy (anytime or not specified)	404 / 378834	Results provided for 'Angiotensin-converting enzyme inhibitors (Ace-i)' as a whole. But as lisinopril represents almost all of the exposures (n=398, 98%), it was considered as equivalent.
Chintamaneni 2018	USA 2003 - 2014 retrospective cohort (claims database)	The Kaiser Permanente Southern California Region, USA.	Pregnant women exposed to angiotensin-converting enzyme inhibitors (Ace-i) during pregnancy were identified using pharmacy dispensing records.		during pregnancy (anytime or not specified)	404 / 378834

Study	Country Study period Study design	Data source	Case	Control	Exposition	Exposition period	Sample size (exposed/unexposed) Or (case / control)	Remarks	Risk of bias

Risk of bias: : NA; : low; : moderate; : serious; : critical; : unclear;