Ondansetron


Study Exclusion reasons Rmk Reference
Karacaer, 2018 other reason

Karacaer J Anesth 2018; 32:90-97 10.1007/s00540-017-2436-x
Terkawi, 2015 other reason EXCLUDED: neonatal and maternal outcomes not exploitable for meta-analysis: provided results are continuous variables (Apgar score ; estimated blood loss)

Terkawi AS Reg Anesth Pain Med 2015;40:344-8 10.1097/AAP.0000000000000274
Asker, 2005 other reason EXCLUDED: OR not calculated for ondansteron and Denominators cannot be retrieved accurately. Of note, all the authors of Danielsson et al., 2014 (also Swedish study on Population databases) were differents that these ones.

Asker C Eur J Clin Pharmacol 2005;61:899-906 10.1007/s00228-005-0055-1
Wang, 2014 other reason EXCLUDED: neonatal outcomes not exploitable for meta-analysis: provided results are continuous variables (Apgar score; Umbilical arterial blood gas analysis and Umbilical venous blood gas analysis).

Wang Q Am J Perinatol 2014;31:913-22 10.1055/s-0033-1364189
Liu, 2015 other reason EXCLUDED: only continuous variables

Liu Y J Tradit Chin Med 2015;35:620-5

Scialli, 2014 review, editorial, news or commentary

Scialli AR Semin Fetal Neonatal Med 2014;19:170-6 10.1016/j.siny.2013.09.007
Koren, 2014 review, editorial, news or commentary

Koren G Ther Drug Monit 2014;: 10.1097/FTD.0000000000000020
Ranjbar, 2018 not relevant outcome

zRanjbar Ginekol. Pol. 2018; 89:453-58 10.5603/GP.a2018.0078
zYeh, 2000 not relevant outcome EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes').

zYeh HM Anesth Analg 2000;91:172-5

zOliveira, 2014 not relevant outcome EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zOliveira LG Obstet Gynecol 2014;124:735-42 10.1097/AOG.0000000000000479
zSullivan, 1996 not relevant outcome EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zSullivan CA Am J Obstet Gynecol 1996;174:1565-8

Abas, 2014 not relevant outcome EXCLUDED: safety outcomes only concerned mothers (no safety data for the neonates). To compare ondansetron with metoclopramide in the treatment of hyperemesis gravidarum.

Abas MN Obstet Gynecol 2014;123:1272-9 10.1097/AOG.0000000000000242
zKoren, 2004 not relevant outcome EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zKoren G J Obstet Gynaecol 2004;24:530-3 10.1080/01443610410001722581
Fejzo, 2013 repeat population groups, duplicate reports (most recent study included) EXCLUDED: data included in a study published after (Fejzo 2016).

Fejzo MS Eur J Obstet Gynecol Reprod Biol 2013;170:71-6 10.1016/j.ejogrb.2013.04.017
zMayhall, 2015 EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zMayhall EA Am J Emerg Med 2015;33:882-6 10.1016/j.ajem.2015.03.032
zZhou, 2018 EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zZhou C J Int Med Res 2018;46:654-662 10.1177/0300060517716502
zHabib, 2013 EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zHabib AS Obstet Gynecol 2013;121:615-23 10.1097/AOG.0b013e3182839fee
zMoser, 2006 EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zMoser JD Ann Pharmacother 2006;40:45-8 10.1345/aph.1G282
zManullang, 2000 EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zManullang TR Anesth Analg 2000;90:1162-6

zLe, 2017 EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zLe TN Am J Perinatol 2017;34:851-855 10.1055/s-0037-1598652
zAbouleish, 1999 EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zAbouleish EI Anaesthesia 1999;54:479-82

zKoju, 2015 EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zKoju RB BMC Anesthesiol 2015;15:18 10.1186/1471-2253-15-18
zPan, 2001 EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zPan PH J Clin Anesth 2001;13:430-5

zEl, 2016 EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zEl Khouly NI Int J Gynaecol Obstet 2016;135:205-209 10.1016/j.ijgo.2016.06.012
zNivatpumin, 2016 EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zNivatpumin P Int J Obstet Anesth 2016;27:25-31 10.1016/j.ijoa.2016.02.003
zBrowning, 2013 EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zBrowning RM Reg Anesth Pain Med 2013;38:39-43 10.1097/AAP.0b013e31827049c6
zKashifard, 2013 EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zKashifard M Clin Exp Obstet Gynecol 2013;40:127-30

zGreer, 2017 EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zGreer KC Reg Anesth Pain Med 2017;42:669-673 10.1097/AAP.0000000000000642
zFattahi, 2015 EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zFattahi Z J Anesth 2015;29:702-7 10.1007/s00540-015-2000-5
zSahoo, 2012 EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zSahoo T Int J Obstet Anesth 2012;21:24-8 10.1016/j.ijoa.2011.08.002
zDemirhan, 2013 EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zDemirhan A Afr Health Sci 2013;13:475-82 10.4314/ahs.v13i2.39
zOrtiz-Gomez, 2014 EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zOrtiz-Gomez JR Int J Obstet Anesth 2014;23:138-43 10.1016/j.ijoa.2014.01.005
zImeh, 2014 EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zImeh A Afr Health Sci 2014;14:453-9 10.4314/ahs.v14i2.23
zSiddik-Sayyid, 2007 EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zSiddik-Sayyid SM Anesth Analg 2007;104:421-4 10.1213/01.ane.0000253668.10453.de
zKlauser, 2011 EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zKlauser CK Am J Perinatol 2011;28:715-21 10.1055/s-0031-1280594
zWells, 2004 EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zWells J Int J Obstet Anesth 2004;13:35-9 10.1016/j.ijoa.2003.07.001
zEl-Deeb, 2011 EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zEl-Deeb AM J Anesth 2011;25:698-703 10.1007/s00540-011-1198-0
zKung, 2014 EXCLUDED: no result related to the safety for pregnancy / foetus / neonate ('Adverse maternal outcomes related to pregnancy' or 'Adverse fetal/neonatal outcomes')

zKung AT Int J Obstet Anesth 2014;23:222-6 10.1016/j.ijoa.2014.04.007
Larrimer, 2014 Studies without separate analysis of the considered drug/class from other drugs/class EXCLUDED: Promethazine and ondansetron analysed together (no separate analysis for ondasetron). Authors conclusion: No clinically significant adverse neurobehavioral effects or obstetric outcomes were identified.

Larrimer MB Am J Obstet Gynecol 2014;210:270.e1-7 10.1016/j.ajog.2014.01.005

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