Anakinra

Study	Exclusion reasons	Rmk	Reference
Viktil (men), 2012	other reason	EXCLUDED: Data related to paternal exposure.	Viktil KK Scand J Rheumatol 2012;41:196-201 10.3109/03009742.2011.626442
Viktil (men), 2009	other reason	EXCLUDED: Data related to paternal exposure.	Viktil KK Pharmacoepidemiol Drug Saf 2009;18:737-42 10.1002/pds.1775
Viktil (women), 2012	Studies without separate analysis of the considered drug/class from other drugs/class	EXCLUDED: Analysis performed on anti-rheumatic drugs as a whole, no individual analyse for each substance. Raw data (number of exposed pregnancies and malformations) were available for were provided in the text and were used for this meta-analysis.	Viktil KK Scand J Rheumatol 2012;41:196-201 10.3109/03009742.2011.626442
Drechsel, 2020	Studies without separate analysis of the considered drug/class from other drugs/class	EXCLUDED: analysis according to DMARD as a whole, with specific data only for TNF and Etanercept but not for other treatments.	Drechsel Rheumatology (Oxford) 2020; 59:603-612 10.1093/rheumatology/kez309
Viktil (women), 2009	pattern of exposure	EXCLUDED: Pattern of exposure without data on fetal/maternal/neonatal safety outcomes.	Viktil KK Pharmacoepidemiol Drug Saf 2009;18:737-42 10.1002/pds.1775