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Cloxazolam / Oxazolam
Overall results
Study description
Excluded studies
Table
Graphic
auto
during pregnancy (anytime or not specified)
1st trimester
2nd trimester
3rd trimester
2nd and/or 3rd trimester
throughout pregnancy
early pregnancy
days before delivery
late pregnancy
preconception-only
periconceptional
preconceptional for kinetic reason
at least 1st trimester
3 months (or more) before pregnancy or during pregnancy
1st and 2nd trimester
3 months or more before pregnancy or1st trimester
Paternal exp. genotoxic window only (0–3 months preconception)
Paternal exposure: epigenetic window only (3–xxx months preconception)
Paternal exposure: genotoxic/epigenetic window (0–xxx months preconception)
Paternal exposure: other window
Whatever the period exposition
individual studies
Outcome
TE
95% CI
n cases
n exposed
k
Pub. bias
Growth parameters and prematurity
Preterm (< 37 weeks)
Meng (Controls unexposed, sick), 2023
1
1.16
[
1.07
; 1.26]
267,218
7,557
not evaluable
Small for gestational age (weight)
Meng (Controls unexposed, sick), 2023
1
1.11
[
1.03
; 1.19]
265,788
7,555
not evaluable
Intrauterine deaths
Late intrauterine deaths (> 22 weeks) / Stillbirths
Meng (Controls unexposed, sick), 2023
1
1.06
[
0.84
; 1.33]
26,200
7,632
not evaluable
Early intrauterine deaths (< 22 weeks) / Spontaneous abortions
Meng, 2024
1
1.54
[
1.27
; 1.86]
-
-
not evaluable
0.8
5.0
1.0