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Rizatriptan
Overall results
Study description
Excluded studies
Table
Graphic
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during pregnancy (anytime or not specified)
1st trimester
2nd trimester
3rd trimester
2nd and/or 3rd trimester
throughout pregnancy
early pregnancy
days before delivery
late pregnancy
preconception-only
periconceptional
preconceptional for kinetic reason
at least 1st trimester
3 months (or more) before pregnancy or during pregnancy
1st and 2nd trimester
3 months or more before pregnancy or1st trimester
Whatever the period exposition
individual studies
Outcome
TE
95% CI
n cases
n exposed
k
Pub. bias
Congenital malformations
All congenital malformations (majors, minors, majors and minors, or unspecified)
Källén (control unexposed, disease free), 2011 Nezvalová-Henriksen (Control unexposed, sick), 2013
2
0.83
[
0.48
; 1.43]
56,797
467
not evaluable
Major congenital malformations
Nezvalová-Henriksen (Control unexposed, sick), 2013
1
0.72
[
0.31
; 1.69]
22
310
not evaluable
Growth parameters and prematurity
Low birth weight (< 2500g)
Nezvalová-Henriksen (Control unexposed, sick), 2013
1
0.75
[
0.37
; 1.52]
33
334
not evaluable
Preterm (< 37 weeks)
Nezvalová-Henriksen (Control unexposed, sick), 2013
1
0.48
[
0.26
; 0.88]
47
334
not evaluable
Small for gestational age (weight)
Nezvalová-Henriksen (Control unexposed, sick), 2013
1
1.19
[
0.69
; 2.03]
61
334
not evaluable
Maternal consequences
Postpartum hemorrhage
Nezvalová-Henriksen (Control unexposed, sick), 2013
1
1.11
[
0.40
; 3.08]
53
26
not evaluable
Neonatal disorders
Neonatal medical care
Nezvalová-Henriksen (Control unexposed, sick), 2013
1
1.58
[
0.51
; 4.91]
32
26
not evaluable
0.2
5.0
1.0
