meta
|
Preg
- medecines during pregnancy KB
Search
Mephenytoin (Epilepsy = ALL)
Overall results
Study description
Excluded studies
Table
Graphic
auto
during pregnancy (anytime or not specified)
1st trimester
2nd trimester
3rd trimester
2nd and/or 3rd trimester
throughout pregnancy
early pregnancy
days before delivery
late pregnancy
preconception-only
periconceptional
preconceptional for kinetic reason
at least 1st trimester
3 months (or more) before pregnancy or during pregnancy
1st and 2nd trimester
3 months or more before pregnancy or1st trimester
Whatever the period exposition
individual studies
Outcome
TE
95% CI
n cases
n exposed
k
Pub. bias
Congenital malformations
All congenital malformations (majors, minors, majors and minors, or unspecified)
Bànhidy (Mephenytoin), 2011
1
0.25
[
0.01
; 6.94]
12
2
not evaluable
Congenital heart defects
Bànhidy (Mephenytoin), 2011
1
0.58
[
0.02
; 16.72]
5
2
not evaluable
Hypospadias
Bànhidy (Mephenytoin), 2011
1
0.90
[
0.03
; 27.86]
3
2
not evaluable
Major congenital malformations
Bànhidy (Mephenytoin), 2011
1
0.25
[
0.01
; 6.94]
12
2
not evaluable
Neural Tube Defects
Bànhidy (Mephenytoin), 2011
1
2.11
[
0.06
; 79.98]
1
2
not evaluable
Polydactyly
Bànhidy (Mephenytoin), 2011
1
1.27
[
0.04
; 41.56]
2
2
not evaluable
Spina bifida
Czeizel (Mephenytoin), 1992
1
0.33
[
0.01
; 12.82]
1
3
not evaluable
0.0
100.0
1.0