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Acebutolol (versus unexposed)
Overall results
Study description
Excluded studies
Table
Graphic
auto
during pregnancy (anytime or not specified)
1st trimester
2nd trimester
3rd trimester
2nd and/or 3rd trimester
throughout pregnancy
early pregnancy
days before delivery
late pregnancy
preconception-only
periconceptional
preconceptional for kinetic reason
at least 1st trimester
3 months (or more) before pregnancy or during pregnancy
1st and 2nd trimester
3 months or more before pregnancy or1st trimester
Whatever the period exposition
individual studies
Outcome
TE
95% CI
n cases
n exposed
k
Pub. bias
Congenital malformations
All congenital malformations (majors, minors, majors and minors, or unspecified)
Delteil, 2024
1
3.55
[
1.27
; 9.86]
4,058
49
not evaluable
Major congenital malformations
Delteil, 2024
1
3.55
[
1.27
; 9.86]
4,058
49
not evaluable
Neonatal disorders
Fetal distress
Yassen, 1992
1
30.33
[
1.39
; 660.79]
6
11
not evaluable
Neonatal bradycardia
Yassen, 1992
1
21.00
[
0.97
; 453.94]
5
11
not evaluable
Neonatal hypoglycemia
Yassen, 1992
1
5.71
[
0.52
; 62.66]
5
11
not evaluable
Neonatal hypotension
Yassen, 1992
1
9.80
[
0.44
; 219.26]
3
11
not evaluable
Neonatal tachypnea
Yassen, 1992
1
9.80
[
0.44
; 219.26]
3
11
not evaluable
0.2
100.0
1.0
