Chlordiazepoxide

Table   Graphic  
individual studies
OutcomeTE95% CIn casesn exposedkPub. bias Congenital malformations All congenital malformations (majors, minors, majors and minors, or unspecified) Hartz, 1975 Kullander, 1976 Bracken, 1981 Czeizel, 2004 Noh, 2022 51.18[0.82; 1.70]184,102738not evaluable Major congenital malformations Kullander, 1976 Bracken, 1981 Czeizel, 2004 Noh, 2022 41.47[1.14; 1.89]181,361476not evaluable Congenital heart defects Rothman, 1979 Czeizel, 2004 Noh, 2022 31.75[0.91; 3.39]88,453389not evaluable Cleft lip with or without cleft palate Czeizel, 1987 Czeizel, 2004 21.12[0.33; 3.81]1,9996not evaluable Cleft palate Czeizel, 1987 Czeizel, 2004 22.01[0.18; 22.38]7763not evaluable Ano-rectal atresia and stenosis Czeizel, 2004 13.00[0.11; 81.44]220-not evaluable Club foot / Talipes equinovarus Czeizel, 2004 11.00[0.30; 3.37]2,420-not evaluable Ear malformations Czeizel, 2004 10.60[0.07; 4.95]351-not evaluable Hydrocephaly Czeizel, 2004 13.00[0.11; 81.44]311-not evaluable Hypospadias Czeizel, 2004 12.20[0.71; 6.81]3,033-not evaluable Limb reduction defects (LRD) Czeizel, 2004 1----- Minor congenital malformations Kullander, 1976 10.55[0.22; 1.36]55187not evaluable Neural Tube Defects Czeizel, 2004 13.00[0.31; 29.29]1,192-not evaluable Oesophageal atresia with or without tracheo-oesophageal fistula Czeizel, 2004 17.00[0.38; 128.84]214-not evaluable Polydactyly Czeizel, 2004 11.20[0.29; 4.95]1,730-not evaluable Growth parameters and prematurity Preterm (< 37 weeks) Meng a (Controls unexposed, sick), 2023 11.04[0.83; 1.31]224,428934not evaluable Small for gestational age (weight) Meng a (Controls unexposed, sick), 2023 11.22[0.99; 1.50]261,229943not evaluable Intrauterine deaths Late intrauterine deaths (> 22 weeks) / Stillbirths Milkovich, 1974 Meng a (Controls unexposed, sick), 2023 21.12[0.65; 1.90]26,7941,129not evaluable Early intrauterine deaths (< 22 weeks) / Spontaneous abortions Milkovich, 1974 Sheehy, 2019 21.62[0.59; 4.46]27,200193not evaluable0.0100.01.0