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Elexacaftor, tezacaftor and ivacaftor (ETI)
Overall results
Study description
Excluded studies
Table
Graphic
auto
during pregnancy (anytime or not specified)
1st trimester
2nd trimester
3rd trimester
2nd and/or 3rd trimester
throughout pregnancy
early pregnancy
days before delivery
late pregnancy
preconception-only
periconceptional
preconceptional for kinetic reason
at least 1st trimester
3 months (or more) before pregnancy or during pregnancy
1st and 2nd trimester
3 months or more before pregnancy or1st trimester
Paternal exp. genotoxic window only (0–3 months preconception)
Paternal exposure: epigenetic window only (3–xxx months preconception)
Paternal exposure: genotoxic/epigenetic window (0–xxx months preconception)
Paternal exposure: other window
Whatever the period exposition
individual studies
Outcome
TE
95% CI
n cases
n exposed
k
Pub. bias
Growth parameters and prematurity
Preterm (< 37 weeks)
Etherington, 2024
1
0.31
[
0.09
; 1.05]
18
26
not evaluable
Maternal consequences
Gestational diabetes
Etherington, 2024
1
3.89
[
1.19
; 12.68]
27
24
not evaluable
0.0
20.0
1.0
