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Domperidone
Overall results
Study description
Excluded studies
Table
Graphic
auto
during pregnancy (anytime or not specified)
1st trimester
2nd trimester
3rd trimester
2nd and/or 3rd trimester
throughout pregnancy
early pregnancy
days before delivery
late pregnancy
preconception-only
periconceptional
preconceptional for kinetic reason
at least 1st trimester
3 months (or more) before pregnancy or during pregnancy
1st and 2nd trimester
3 months or more before pregnancy or1st trimester
Whatever the period exposition
individual studies
Outcome
TE
95% CI
n cases
n exposed
k
Pub. bias
Congenital malformations
All congenital malformations (majors, minors, majors and minors, or unspecified)
Choi, 2013 Cottin (Controls unexposed, disease free), 2015
2
1.10
[
0.36
; 3.39]
14
232
not evaluable
Major congenital malformations
Choi, 2013 Cottin (Controls unexposed, disease free), 2015
2
1.10
[
0.36
; 3.39]
14
232
not evaluable
Neonatal disorders
Jaundice / Icterus
Choi, 2013
1
0.43
[
0.05
; 3.51]
5
120
not evaluable
Intrauterine deaths
Early intrauterine death (< 22 weeks)
Choi, 2013 Cottin (Controls unexposed, disease free), 2015
2
0.94
[
0.46
; 1.91]
37
244
not evaluable
Elective/induced termination of pregnancy
Cottin (Controls unexposed, disease free), 2015
1
1.12
[
0.37
; 3.40]
14
124
not evaluable
Neuro-developmental disorders
Neuro-developmental disorders (as a whole)
Fejzo, 2015
1
2.54
[
0.23
; 28.35]
138
3
not evaluable
0.0
50.0
1.0
