Interferon beta 1a (IFN-beta1a)

Table   Graphic  
individual studies
OutcomeTE95% CIn casesn exposedkPub. bias Congenital malformations All congenital malformations (majors, minors, majors and minors, or unspecified) Weber-Schoendorfer (control unexposed, sick), 2009 10.55[0.10; 2.97]740not evaluable Major congenital malformations Weber-Schoendorfer (control unexposed, sick), 2009 10.19[0.01; 3.85]340not evaluable Congenital cataract 0----- Growth parameters and prematurity Preterm (< 37 weeks) Weber-Schoendorfer (control unexposed, sick), 2009 Fragoso a (control unexposed, sick), 2013 Nguyen (control unexposed, sick), 2019 31.16[0.45; 2.99]249292not evaluable Maternal consequences Preeclampsia Fragoso a (control unexposed, sick), 2013 11.10[0.11; 10.95]429not evaluable Gestational diabetes Fragoso a (control exposed to Glatiramer), 2013 10.44[0.02; 11.17]129not evaluable Neonatal disorders Jaundice / Icterus Fragoso a (control unexposed, sick), 2013 10.81[0.16; 4.02]1029not evaluable Long term consequences Child/Infant infections (> 1 year) Fragoso a (control unexposed, sick), 2013 13.75[1.00; 14.02]1029not evaluable Child/Infant weight abnormalities (> 1 year) Fragoso a (control unexposed, sick), 2013 13.36[0.20; 55.42]229not evaluable Intrauterine deaths Intrauterine deaths (as a whole or unspecified) Weber-Schoendorfer (control unexposed, sick), 2009 Nguyen (control unexposed, sick), 2019 20.73[0.41; 1.31]71292not evaluable Elective/induced termination of pregnancy Nguyen (control unexposed, sick), 2019 11.62[0.83; 3.13]41250not evaluable Neuro-developmental disorders Psychomotor developmental disorders/delay Fragoso a (control unexposed, sick), 2013 110.31[0.41; 260.28]129not evaluable ASD (Autism spectrum disorder): Diagnosis Fragoso a (control unexposed, sick), 2013 110.31[0.41; 260.28]129not evaluable ASD (Autism spectrum disorder): Diagnosis/Risk Fragoso a (control unexposed, sick), 2013 110.31[0.41; 260.28]129not evaluable ADHD (Attention deficit hyperactivity disorder): Diagnosis Fragoso a (control unexposed, sick), 2013 10.65[0.03; 13.92]229not evaluable ADHD (Attention deficit hyperactivity disorder): Diagnosis/Risk Fragoso a (control unexposed, sick), 2013 10.65[0.03; 13.92]229not evaluable Cognitive developmental disorders/delay (> 6 years old) Fragoso a (control unexposed, sick), 2013 11.66[0.15; 19.00]329not evaluable Language disorders/delay Fragoso a (control exposed to Glatiramer), 2013 10.44[0.02; 11.17]129not evaluable Learning disorders Fragoso a (control unexposed, sick), 2013 11.09[0.04; 27.59]129not evaluable0.0100.01.0