Ethosuximide (Epilepsy)

Table   Graphic  
individual studies
OutcomeTE95% CIn casesn exposedkPub. bias Congenital malformations All congenital malformations (majors, minors, majors and minors, or unspecified) Samrén (Ethosuximide), 1999 Dean (Ethosuximide), 2002 Kaaja (Ethosuximide), 2003 Morrow (Ethosuximide) (Controls unexposed, sick), 2006 Bànhidy (Ethosuximide), 2011 Vajda (Ethosuximide) (Controls unexposed, sick), 2019 Battino, 2024 72.49[0.83; 7.52]17652not evaluable Major congenital malformations Samrén (Ethosuximide), 1999 Dean (Ethosuximide), 2002 Kaaja (Ethosuximide), 2003 Morrow (Ethosuximide) (Controls unexposed, sick), 2006 Bànhidy (Ethosuximide), 2011 Vajda (Ethosuximide) (Controls unexposed, sick), 2019 Battino, 2024 72.74[0.86; 8.73]17052not evaluable Congenital heart defects Morrow (Ethosuximide) (Controls exposed to Lamotrigine, sick), 2006 16.21[0.32; 122.15]412not evaluable Hypospadias Morrow (Ethosuximide) (Controls exposed to Lamotrigine, sick), 2006 14.28[0.23; 80.64]612not evaluable Microcephaly / Small head circumference for gestational age Christensen (Ethosuximide) (Epilepsy) (Controls unexposed, general population), 2024 11.47[0.09; 25.04]69911not evaluable Neural Tube Defects Morrow (Ethosuximide) (Controls exposed to Lamotrigine, sick), 2006 118.71[0.72; 484.16]112not evaluable Digestive system anomalies Morrow (Ethosuximide) (Controls exposed to Lamotrigine, sick), 2006 17.99[0.39; 163.81]312not evaluable Eye defects Dean (Ethosuximide), 2002 15.33[0.29; 97.49]72not evaluable Limb defects Morrow (Ethosuximide) (Controls exposed to Lamotrigine, sick), 2006 111.21[0.51; 246.80]212not evaluable Minor congenital malformations Dean (Ethosuximide), 2002 12.20[0.19; 25.52]64not evaluable Oro-facial clefts Morrow (Ethosuximide) (Controls exposed to Lamotrigine, sick), 2006 118.71[0.72; 484.16]112not evaluable Polydactyly 0----- Neonatal disorders Withdrawal syndrome / Neonatal abstinence syndrome / Poor neonatal adaptation 0----- Intrauterine deaths Intrauterine deaths (as a whole or unspecified) Vajda a (Ethosuximide) (Controls unexposed sick), 2024 1----- Neuro-developmental disorders Neuro-developmental disorders (as a whole) Dean (Ethosuximide), 2002 18.50[0.44; 163.89]52not evaluable0.0100.01.0

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