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Acetazolamide (All indications)
Overall results
Study description
Excluded studies
Table
Graphic
auto
during pregnancy (anytime or not specified)
1st trimester
2nd trimester
3rd trimester
2nd and/or 3rd trimester
throughout pregnancy
early pregnancy
days before delivery
late pregnancy
preconception-only
periconceptional
preconceptional for kinetic reason
at least 1st trimester
3 months (or more) before pregnancy or during pregnancy
1st and 2nd trimester
3 months or more before pregnancy or1st trimester
Whatever the period exposition
individual studies
Outcome
TE
95% CI
n cases
n exposed
k
Pub. bias
Congenital malformations
All congenital malformations (majors, minors, majors and minors, or unspecified)
Samrén (Acetazolamide), 1999 Vajda (Acetazolamide) (Controls unexposed, sick), 2019 Battino (Acetazolamide) (Epilepsy), 2024
3
24.39
[
2.95
; 201.78]
145
4
not evaluable
Major congenital malformations
Samrén (Acetazolamide), 1999 Vajda (Acetazolamide) (Controls unexposed, sick), 2019 Battino (Acetazolamide) (Epilepsy), 2024
3
24.39
[
2.95
; 201.78]
145
4
not evaluable
Microcephaly / Small head circumference for gestational age
Christensen (Acetazolamide) (All indications) (Controls unexposed, general population), 2024
1
0.13
[
0.01
; 2.05]
134,023
127
not evaluable
Growth parameters and prematurity
Small for gestational age (weight)
Christensen (Acetazolamide) (All indications) (Controls unexposed, general population), 2024
1
1.00
[
0.58
; 1.73]
446,282
127
not evaluable
0.0
100.0
1.0
