meta
|
Preg
- medecines during pregnancy KB
Search
Dosulepin / Dothiepin
Overall results
Study description
Excluded studies
Table
Graphic
auto
during pregnancy (anytime or not specified)
1st trimester
2nd trimester
3rd trimester
2nd and/or 3rd trimester
throughout pregnancy
early pregnancy
days before delivery
late pregnancy
preconception-only
periconceptional
preconceptional for kinetic reason
at least 1st trimester
3 months (or more) before pregnancy or during pregnancy
1st and 2nd trimester
3 months or more before pregnancy or1st trimester
Paternal exp. genotoxic window only (0–3 months preconception)
Paternal exposure: epigenetic window only (3–xxx months preconception)
Paternal exposure: genotoxic/epigenetic window (0–xxx months preconception)
Paternal exposure: other window
Whatever the period exposition
individual studies
Outcome
TE
95% CI
n cases
n exposed
k
Pub. bias
Congenital malformations
All congenital malformations (majors, minors, majors and minors, or unspecified)
Chan (Controls unexposed, general pop), 2024
1
1.35
[
0.55
; 3.32]
22,633
83
not evaluable
Congenital heart defects
Chan (Controls unexposed, general pop), 2024
1
2.29
[
0.72
; 7.27]
8,110
83
not evaluable
Major congenital malformations
Chan (Controls unexposed, general pop), 2024
1
1.35
[
0.55
; 3.32]
22,633
83
not evaluable
Growth parameters and prematurity
Large for gestational age (weight)
Lee (Controls unexposed, general pop), 2025
1
0.95
[
0.30
; 3.00]
9,747
131
not evaluable
Low birth weight (< 2500g)
Lee (Controls unexposed, general pop), 2025
1
1.54
[
0.93
; 2.55]
31,365
131
not evaluable
Preterm (< 37 weeks)
Lee (Controls unexposed, general pop), 2025
1
0.97
[
0.52
; 1.81]
28,554
131
not evaluable
Small for gestational age (weight)
Lee (Controls unexposed, general pop), 2025
1
1.89
[
0.69
; 5.17]
6,990
131
not evaluable
Maternal consequences
Assisted deliveries (forceps, vacuum, ...)
Lee (Controls unexposed, general pop), 2025
1
0.60
[
0.26
; 1.37]
46,042
131
not evaluable
Caesarean
Lee (Controls unexposed, general pop), 2025
1
0.85
[
0.58
; 1.24]
111,678
131
not evaluable
Maternal consequences (as a whole)
Lee (Controls unexposed, general pop), 2025
1
0.91
[
0.63
; 1.32]
311,183
131
not evaluable
Postpartum hemorrhage
Lee (Controls unexposed, general pop), 2025
1
0.64
[
0.20
; 2.03]
19,758
131
not evaluable
Neonatal disorders
Low Apgar score (< 7) (at 1 min)
Lee (Controls unexposed, general pop), 2025
1
1.35
[
0.63
; 2.90]
14,890
131
not evaluable
Low Apgar score (< 7) (at 5 min)
Lee (Controls unexposed, general pop), 2025
1
1.65
[
0.72
; 3.78]
1,722
131
not evaluable
Neonatal death (< 28 days of life)
Lee (Controls unexposed, general pop), 2025
1
2.83
[
0.18
; 45.47]
627
131
not evaluable
Neonatal disorders (as a whole)
Lee (Controls unexposed, general pop), 2025
1
2.14
[
1.51
; 3.04]
161,484
131
not evaluable
Neonatal medical care
Lee (Controls unexposed, general pop), 2025
1
0.87
[
0.28
; 2.73]
8,569
131
not evaluable
Long term consequences
Child/Infant death (> 28 days of life)
Lee (Controls unexposed, general pop), 2025
1
13.60
[
0.84
; 219.80]
130
131
not evaluable
Neuro-developmental disorders
ASD (Autism spectrum disorder): Diagnosis
Heuvelman, 2023
1
1.53
[
0.73
; 3.20]
-
451
not evaluable
ASD (Autism spectrum disorder): Diagnosis/Risk
Heuvelman, 2023
1
1.53
[
0.73
; 3.20]
-
451
not evaluable
0.0
100.0
1.0
