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Semaglutide
Overall results
Study description
Excluded studies
Table
Graphic
auto
during pregnancy (anytime or not specified)
1st trimester
2nd trimester
3rd trimester
2nd and/or 3rd trimester
throughout pregnancy
early pregnancy
days before delivery
late pregnancy
preconception-only
periconceptional
preconceptional for kinetic reason
at least 1st trimester
3 months (or more) before pregnancy or during pregnancy
1st and 2nd trimester
3 months or more before pregnancy or1st trimester
Paternal exp. genotoxic window only (0–3 months preconception)
Paternal exposure: epigenetic window only (3–xxx months preconception)
Paternal exposure: genotoxic/epigenetic window (0–xxx months preconception)
Paternal exposure: other window
Whatever the period exposition
individual studies
Outcome
TE
95% CI
n cases
n exposed
k
Pub. bias
Congenital malformations
All congenital malformations (majors, minors, majors and minors, or unspecified)
Kolding (Controls unexposed, general pop), 2025
1
1.24
[
0.30
; 5.07]
7,988
32
not evaluable
Major congenital malformations
Kolding (Controls unexposed, general pop), 2025
1
1.24
[
0.30
; 5.07]
7,988
32
not evaluable
Growth parameters and prematurity
Preterm (< 37 weeks)
Kolding (Controls unexposed, general pop), 2025
1
4.95
[
1.80
; 13.59]
4,852
30
not evaluable
Large for gestational age (weight)
Kolding (Controls unexposed, general pop), 2025
1
5.94
[
2.16
; 16.36]
4,190
29
not evaluable
Small for gestational age (weight)
Kolding (Controls unexposed, general pop), 2025
1
0.17
[
0.01
; 2.74]
9,447
29
not evaluable
Maternal consequences
Caesarean
0
-
-
-
-
-
Gestational diabetes
0
-
-
-
-
-
Preeclampsia
0
-
-
-
-
-
Neonatal disorders
Jaundice / Icterus
Kolding (Controls unexposed, general pop), 2025
1
3.31
[
1.11
; 9.90]
5,952
29
not evaluable
Neonatal hypoglycemia
Kolding (Controls unexposed, general pop), 2025
1
7.89
[
1.92
; 32.39]
1,451
29
not evaluable
Neonatal medical care
0
-
-
-
-
-
0.0
50.0
1.0
