Infliximab

Table   Graphic  
individual studies
OutcomeTE95% CIn casesn exposedkPub. bias Congenital malformations All congenital malformations (majors, minors, majors and minors, or unspecified) Hyrich, 2006 Weber-Schoendorfer, 2015 De Lorenzo (Controls unexposed, sick), 2020 33.30[1.43; 7.61]28161not evaluable Major congenital malformations Hyrich, 2006 Weber-Schoendorfer, 2015 23.11[1.32; 7.31]28158not evaluable Growth parameters and prematurity Preterm (< 37 weeks) De Lorenzo (Controls unexposed, sick), 2020 11.63[0.06; 41.29]33not evaluable Small for gestational age (weight) De Lorenzo (Controls unexposed, sick), 2020 17.50[0.46; 122.70]33not evaluable Macrosomia (> 4000g) De Lorenzo (Controls unexposed, sick), 2020 112.60[0.20; 780.42]-3not evaluable Maternal consequences Caesarean 0----- Neonatal disorders Neonatal infections Vinet (Unexposed controls, sick), 2018 14.37[1.30; 14.71]5237not evaluable Neonatal disorders (as a whole) 0----- Neonatal medical care 0----- Intrauterine deaths Elective/induced termination of pregnancy Hyrich, 2006 13.40[0.05; 219.14]-3not evaluable Early intrauterine death (< 22 weeks) Hyrich, 2006 14.00[0.17; 95.76]23not evaluable Intrauterine deaths (as a whole or unspecified) 0----- Late intrauterine deaths (> 22 weeks) 0----- Therapeutic terminations of pregnancy 0-----0.0100.01.0