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Zolmitriptan
Overall results
Study description
Excluded studies
Table
Graphic
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during pregnancy (anytime or not specified)
1st trimester
2nd trimester
3rd trimester
2nd and/or 3rd trimester
throughout pregnancy
early pregnancy
days before delivery
late pregnancy
preconception-only
periconceptional
preconceptional for kinetic reason
at least 1st trimester
3 months (or more) before pregnancy or during pregnancy
1st and 2nd trimester
3 months or more before pregnancy or1st trimester
Whatever the period exposition
individual studies
Outcome
TE
95% CI
n cases
n exposed
k
Pub. bias
Congenital malformations
All congenital malformations (majors, minors, majors and minors, or unspecified)
Källén (control unexposed, disease free), 2011 Nezvalová-Henriksen (Control unexposed, sick), 2013
2
0.95
[
0.52
; 1.74]
56,790
506
not evaluable
Major congenital malformations
Nezvalová-Henriksen (Control unexposed, sick), 2013
1
1.86
[
0.53
; 6.51]
11
144
not evaluable
Growth parameters and prematurity
Low birth weight (< 2500g)
Nezvalová-Henriksen (Control unexposed, sick), 2013
1
1.35
[
0.53
; 3.45]
19
156
not evaluable
Preterm (< 37 weeks)
Nezvalová-Henriksen (Control unexposed, sick), 2013
1
0.96
[
0.44
; 2.08]
28
156
not evaluable
Small for gestational age (weight)
Nezvalová-Henriksen (Control unexposed, sick), 2013
1
1.15
[
0.50
; 2.65]
24
156
not evaluable
Maternal consequences
Postpartum hemorrhage
Nezvalová-Henriksen (Control unexposed, sick), 2013
1
0.61
[
0.13
; 2.81]
29
17
not evaluable
Neonatal disorders
Neonatal medical care
Nezvalová-Henriksen (Control unexposed, sick), 2013
1
3.89
[
1.08
; 13.95]
15
17
not evaluable
0.0
20.0
1.0